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C 反应蛋白和白细胞介素-8 对异基因造血干细胞移植后发热性中性粒细胞减少症患儿风险分层的诊断价值。

Diagnostic Value of C-reactive Protein and Interleukin-8 in Risk Stratification of Febrile Neutropenic Children with Allogeneic Hematopoietic Stem Cell Transplantation.

机构信息

Division of Hematology/Oncology, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University, Linkou, Taoyuan, Taiwan.

Department of Medical Imaging and Intervention, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan.

出版信息

Sci Rep. 2020 Feb 19;10(1):2894. doi: 10.1038/s41598-020-59814-6.

DOI:10.1038/s41598-020-59814-6
PMID:32076032
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7031361/
Abstract

In this analysis, the levels of CRP and IL-8 were employed as a guide for designing the duration of antibiotics administration in the condition of febrile neutropenia. The importance of laboratory biomarkers is in the early diagnosis of critical illness and adjustment of further management. IL-8 is a useful biomarker for the early identification of critically ill patients, compared to CRP in FN.

摘要

在本分析中，CRP 和 IL-8 的水平被用作指导，以设计发热性中性粒细胞减少症时抗生素治疗的持续时间。实验室生物标志物的重要性在于对危重病的早期诊断和进一步治疗的调整。与 FN 中的 CRP 相比，IL-8 是一种用于早期识别危重病患者的有用生物标志物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/886a/7031361/bc340f77e217/41598_2020_59814_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/886a/7031361/bc340f77e217/41598_2020_59814_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/886a/7031361/bc340f77e217/41598_2020_59814_Fig1_HTML.jpg

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本文引用的文献

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Diagnostic value of sTREM-1, IL-8, PCT, and CRP in febrile neutropenia after autologous stem cell transplantation.可溶性髓系细胞触发受体-1、白细胞介素-8、降钙素原和C反应蛋白在自体干细胞移植后发热性中性粒细胞减少症中的诊断价值
Ann Hematol. 2017 Dec;96(12):2095-2101. doi: 10.1007/s00277-017-3128-1. Epub 2017 Sep 17.
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The evolution of allogeneic stem cell transplant for children and adolescents with acute myeloid leukemia.儿童和青少年急性髓系白血病异基因干细胞移植的发展历程。
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Diagnostic value of sepsis biomarkers in hematopoietic stem cell transplant recipients in a condition of high prevalence of gram-negative pathogens.
革兰氏阴性病原体高流行情况下造血干细胞移植受者中脓毒症生物标志物的诊断价值
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Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012.拯救脓毒症运动：严重脓毒症和脓毒性休克管理国际指南，2012 年。
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