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SF3B1 mutations induce R-loop accumulation and DNA damage in MDS and leukemia cells with therapeutic implications.

作者信息

Singh Shalini, Ahmed Doaa, Dolatshad Hamid, Tatwavedi Dharamveer, Schulze Ulrike, Sanchi Andrea, Ryley Sarah, Dhir Ashish, Carpenter Lee, Watt Suzanne M, Roberts David J, Abdel-Aal Amal M, Sayed Sohair K, Mohamed Somaia A, Schuh Anna, Vyas Paresh, Killick Sally, Kotini Andriana G, Papapetrou Eirini P, Wiseman Daniel H, Pellagatti Andrea, Boultwood Jacqueline

机构信息

Bloodwise Molecular Haematology Unit, Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford, Oxford, UK.

Clinical Pathology Department, Assiut University, Assiut, Egypt.

出版信息

Leukemia. 2020 Sep;34(9):2525-2530. doi: 10.1038/s41375-020-0753-9. Epub 2020 Feb 19.

Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4815/7449882/994aad1d3b4e/41375_2020_753_Fig1_HTML.jpg

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