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采用缝线牵拉技术行后弹力层剥除自动角膜内皮移植术治疗的一名Pearson骨髓-胰腺综合征患儿的内皮功能障碍

Endothelial dysfunction in a child with Pearson marrow-pancreas syndrome managed with Descemet stripping automated endothelial keratoplasty using a suture pull-through technique.

作者信息

Vadhul Raghav, Halbach Caroline S, Areaux Raymond G, Berry Susan, Hou Joshua H

机构信息

Indiana University School of Medicine, Indianapolis.

Department of Ophthalmology and Visual Neurosciences, University of Minnesota, Minneapolis.

出版信息

Digit J Ophthalmol. 2019 Nov 17;25(4):59-64. doi: 10.5693/djo.02.2019.09.001. eCollection 2019 Apr.

Abstract

A 4-year-old girl with a history of Pearson marrow-pancreas syndrome presenting with severe, progressive photophobia was found to have bilateral, diffuse corneal thickening and peripheral pigmentary retinopathy. She underwent Descemet stripping automated endothelial keratoplasty (DSAEK) surgery in both eyes using a modified suture pull-through technique. Postoperatively there was no evidence of cataract formation or graft detachment; her corneas thinned, and her photophobia improved dramatically.

摘要

一名患有皮尔逊骨髓-胰腺综合征的4岁女孩,出现严重的进行性畏光症状,被发现双眼弥漫性角膜增厚及周边色素性视网膜病变。她双眼接受了使用改良缝线牵拉技术的后弹力层剥除自动角膜内皮移植术(DSAEK)。术后未发现白内障形成或移植物脱离的迹象;她的角膜变薄,畏光症状显著改善。

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本文引用的文献

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Pediatric corneal transplants.小儿角膜移植
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Challenges in pediatric endothelial keratoplasty.小儿内皮角膜移植术的挑战。
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Descemet stripping automated endothelial keratoplasty in pediatric age group.小儿年龄组的后弹力层剥除自动内皮角膜移植术
Saudi J Ophthalmol. 2012 Jul;26(3):309-13. doi: 10.1016/j.sjopt.2012.04.006. Epub 2012 May 12.
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Corneal endothelial dysfunction in Pearson syndrome.皮尔逊综合征中的角膜内皮功能障碍。
Ophthalmic Genet. 2013 Mar-Jun;34(1-2):55-7. doi: 10.3109/13816810.2011.610862. Epub 2011 Sep 21.
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Molecular mechanisms underlying the corneal endothelial pump.角膜内皮泵的分子机制。
Exp Eye Res. 2012 Feb;95(1):2-7. doi: 10.1016/j.exer.2011.06.004. Epub 2011 Jun 15.

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