乌干达坎帕拉穆拉戈医院尿路感染患者中[病原体名称]的流行情况及其药敏谱
Prevalence of and Its Antimicrobial Susceptibility Profiles among Patients with UTI at Mulago Hospital, Kampala, Uganda.
作者信息
Odongo Isaac, Ssemambo Ronald, Kungu Joseph M
机构信息
College of Veterinary Medicine, Animal Resources and Biosecurity Makerere University, P. O. Box 7062, Kampala, Uganda.
出版信息
Interdiscip Perspect Infect Dis. 2020 Feb 1;2020:8042540. doi: 10.1155/2020/8042540. eCollection 2020.
BACKGROUND
Urinary tract infections (UTIs) remain the most common infections diagnosed in in- and outpatients as well as hospitalized patients. Current knowledge on antimicrobial susceptibility pattern for uropathogens is essential to effectively manage UTIs. This study aimed at determining the prevalence of and its antimicrobial susceptibility profiles among patients presenting with signs and symptoms of UTI in Mulago Hospital in Uganda.
METHODS
Midstream urine samples were collected from 100 patients presenting with signs and symptoms of UTI at the outpatient department of Mulago Hospital. The samples were cultured, and isolates of and its antimicrobial susceptibility profiles among patients presenting with signs and symptoms of UTI in Mulago Hospital in Uganda.
RESULTS
Out of 100 patients studied, and its antimicrobial susceptibility profiles among patients presenting with signs and symptoms of UTI in Mulago Hospital in Uganda. isolates were highly susceptible to cefotaxime/clavulanic acid (100%) and nitrofurantoin (70%) but showed high resistance to cefuroxime (100%), ceftazidime (100%), nalidixic acid (90%), and ciprofloxacin (90%).
CONCLUSION
, the predominant uropathogen, showed significant multidrug resistance to antibiotics commonly prescribed for the management of UTIs. These findings should form a basis for preliminary decision making on the appropriate line of treatment for UTIs. isolates were highly susceptible to cefotaxime/clavulanic acid (100%) and nitrofurantoin (70%) but showed high resistance to cefuroxime (100%), ceftazidime (100%), nalidixic acid (90%), and ciprofloxacin (90%).
背景
尿路感染（UTIs）仍然是门诊、住院患者中诊断出的最常见感染。了解当前尿路病原体的抗菌药物敏感性模式对于有效管理尿路感染至关重要。本研究旨在确定乌干达穆拉戈医院出现尿路感染症状和体征的患者中[病原体名称未给出]的流行情况及其抗菌药物敏感性谱。
方法
从穆拉戈医院门诊部100例出现尿路感染症状和体征的患者中采集中段尿样本。对样本进行培养，并确定乌干达穆拉戈医院出现尿路感染症状和体征的患者中[病原体名称未给出]的分离株及其抗菌药物敏感性谱。
结果
在研究的100例患者中，乌干达穆拉戈医院出现尿路感染症状和体征的患者中[病原体名称未给出]的分离株对头孢噻肟/克拉维酸（100%）和呋喃妥因（70%）高度敏感，但对头孢呋辛（100%）、头孢他啶（100%）、萘啶酸（90%）和环丙沙星（90%）表现出高耐药性。
结论
[病原体名称未给出]作为主要的尿路病原体，对常用于治疗尿路感染的抗生素表现出显著的多重耐药性。这些发现应为尿路感染适当治疗方案的初步决策提供依据。[病原体名称未给出]的分离株对头孢噻肟/克拉维酸（100%）和呋喃妥因（70%）高度敏感，但对头孢呋辛（100%）、头孢他啶（100%）、萘啶酸（90%）和环丙沙星（90%）表现出高耐药性。
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