Shribman Samuel E, Katanga Jessica, Ali Nadeem, Hayman Grant R, Bridges Leslie R, Habibi Maximillian S, Mackinnon Andrew D, Nitkunan Arani
Department of Neurology, St George's Hospital, London, England.
St George's University of London, London, England.
Neuroophthalmology. 2018 Nov 13;44(1):38-40. doi: 10.1080/01658107.2018.1542008. eCollection 2020 Feb.
Common variable immunodeficiency is the most common primary immunodeficiency and rarely causes neurological manifestations since the introduction of IVIg, but here, the authors present a case of a 31-year-old Afro-Caribbean man who after short non-adherence to his immunoglobulins, develops encephalomyelitis with retinopathy. To the authors' knowledge, this is the first case presented with retinal photographs, OCT, CT, MRI and brain biopsies.
普通可变免疫缺陷是最常见的原发性免疫缺陷，自静脉注射免疫球蛋白应用以来很少引起神经学表现，但在此，作者报告了一例31岁的非洲加勒比裔男性病例，该患者在短期未坚持使用免疫球蛋白后，发生了伴有视网膜病变的脑脊髓炎。据作者所知，这是首例呈现视网膜照片、光学相干断层扫描（OCT）、计算机断层扫描（CT）、磁共振成像（MRI）及脑活检结果的病例。
