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类风湿关节炎初次非骨水泥全髋关节置换术后髋臼杯迁移及其影响因素:与骨关节炎髋关节的对比研究。

Acetabular cup migration after primary cementless total hip arthroplasty in rheumatoid arthritis and its influencing factors: a comparative study with osteoarthritic hip.

机构信息

Department of Orthopedic Surgery, Hanyang University Guri Hospital, Gyomoon-dong 249-1, Guri, Gyunggi-do, 471-701, South Korea.

Department of Orthopedic Surgery, Hanyang University Hospital, Seoul, South Korea.

出版信息

Int Orthop. 2020 Jun;44(6):1047-1053. doi: 10.1007/s00264-020-04502-3. Epub 2020 Feb 19.

Abstract

PURPOSE

To compare the radiographic migration profiles of primary cementless total hip arthroplasty (THA) between patients with rheumatoid arthritis (RA) and those with osteoarthritis (OA).

METHODS

A total of 197 patients (215 hips) who underwent cementless THA for RA or OA between January 2001 and January 2013 and followed up for a minimum of 5.5 years were included. Ninety-four RA patients (109 hips) were compared with 103 OA patients (106 hips). Radiological evaluation was performed for acetabular cup loosening, and cup migration was measured using Einzel-Bild-Röntgen-Analyse (EBRA) software. Multiple variables were assessed to identify influencing factors for cup migration.

RESULTS

Early cup migration was observed in 13 hips (11.9%) in the RA group and four hips (3.8%) in the OA group, showing a significant difference (p = 0.041). Acetabular cup loosening occurred in three cups (2.8%) in the RA group and in one cup (0.9%) in the OA group, showing no significant difference (p = 0.321). Total cup migration was higher in the RA group (2.62 mm) than in the OA group (1.44 mm, p = 0.005). Total cup migration was significantly higher in patients aged < 50 years than in those aged > 50 years (p = 0.005). Rheumatoid factor (RF) and anti-cyclic citrullinated peptide (anti-CCP) antibody influenced total cup migration. Patients with seropositive RA showed significantly higher total cup migration and early cup migration incidence than those with seronegative RA (p = 0.005, p = 0.038, respectively).

CONCLUSIONS

Acetabular cups in primary cementless THAs of RA patients were less stable in terms of cup migration compared with that of OA patients.

摘要

目的

比较类风湿关节炎(RA)和骨关节炎(OA)患者初次非骨水泥全髋关节置换术(THA)的放射学迁移曲线。

方法

共纳入 2001 年 1 月至 2013 年 1 月期间接受初次非骨水泥 THA 治疗的 RA 或 OA 患者 197 例(215 髋),随访时间至少 5.5 年。94 例 RA 患者(109 髋)与 103 例 OA 患者(106 髋)进行比较。采用单幅 X 线分析(EBRA)软件评估髋臼杯松动情况,并测量髋臼杯迁移。评估多个变量以确定影响髋臼杯迁移的因素。

结果

RA 组 13 髋(11.9%)和 OA 组 4 髋(3.8%)出现早期髋臼杯迁移,差异有统计学意义(p=0.041)。RA 组 3 髋(2.8%)和 OA 组 1 髋(0.9%)出现髋臼杯松动,差异无统计学意义(p=0.321)。RA 组总髋臼杯迁移(2.62mm)高于 OA 组(1.44mm,p=0.005)。年龄<50 岁的患者总髋臼杯迁移明显高于年龄>50 岁的患者(p=0.005)。类风湿因子(RF)和抗环瓜氨酸肽(anti-CCP)抗体影响总髋臼杯迁移。血清阳性 RA 患者的总髋臼杯迁移和早期髋臼杯迁移发生率明显高于血清阴性 RA 患者(p=0.005,p=0.038)。

结论

初次非骨水泥 THA 中,RA 患者的髋臼杯在髋臼杯迁移方面较 OA 患者更不稳定。

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