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钯催化的对溴苯甲醛、对甲苯磺酰腙和甲醇的三组分偶联反应。

Palladium-Catalyzed Three-Component Coupling Reaction of -Bromobenzaldehyde, -Tosylhydrazone, and Methanol.

作者信息

Zhu Lei, Ren Xiaojian, Yu Yinghua, Ou Pengcheng, Wang Zhi-Xiang, Huang Xueliang

机构信息

Key Laboratory of Coal to Ethylene Glycol and Its Related Technology, Center for Excellence in Molecular Synthesis, Fujian Institute of Research on the Structure of Matter, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Fuzhou, Fujian 350002, China.

School of Chemical Sciences, University of the Chinese Academy of Sciences, Beijing 100049, China.

出版信息

Org Lett. 2020 Mar 6;22(5):2087-2092. doi: 10.1021/acs.orglett.0c00579. Epub 2020 Feb 20.

Abstract

A ligand-controlled palladium-catalyzed three-component reaction of -bromobenzaldehyde, -tosylhydrazone, and methanol is described. This reaction uses readily available compounds as starting materials while displaying a broad substrate scope and good functional group compatibility.

摘要

描述了一种配体控制的钯催化的α-溴苯甲醛、α-甲苯磺酰腙和甲醇的三组分反应。该反应使用容易获得的化合物作为起始原料,同时具有广泛的底物范围和良好的官能团兼容性。

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