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创伤患者复苏中的骨髓内通路:文献复习。

Intraosseous access in the resuscitation of trauma patients: a literature review.

机构信息

Department of Anaesthetics, Russells Hall Hospital, Pensnett Road, Dudley, DY1 2HQ, UK.

Centre for Trauma Sciences, Blizard Institute, Queen Mary University of London, 4 Newark Street, London, E1 2AT, UK.

出版信息

Eur J Trauma Emerg Surg. 2021 Feb;47(1):47-55. doi: 10.1007/s00068-020-01327-y. Epub 2020 Feb 20.

Abstract

PURPOSE

Intraosseous (IO) catheters continue to be recommended in trauma resuscitation. Their utility has recently been debated due to concerns regarding inadequate flow rates during blood transfusion, and the potential for haemolysis. The objective of this review was to examine the evidence for intraosseous catheters in trauma resuscitation, and to highlight areas for future research.

METHODS

A PubMed and Embase search for articles published from January 1990 to August 2018 using the terms ("intra-osseous access" or "intraosseous access" or "IO access") AND trauma was performed. Original articles describing the use of an IO catheter in the resuscitation of one or more trauma patients were eligible. Animal, cadaveric studies and those involving healthy volunteers were excluded.

RESULTS

Nine studies, comprising of 1218 trauma patients and 1432 device insertions, were included. The insertion success rate was 95% and the incidence of complications 0.9%. Flow-rate data and evidence of haemolysis were poorly reported.

CONCLUSION

Intraosseous catheters have high insertion success rates and a low incidence of complications in trauma patients. Existing evidence suggests that IO transfusion is not associated with haemolysis, however, further studies in humans are needed. There is a paucity of flow rate data for blood transfusion via IO catheters in this population, although much anecdotal evidence advocating their use exists.

摘要

目的

在创伤复苏中,继续推荐使用骨髓内(IO)导管。由于担心输血期间流量不足以及潜在的溶血,最近对其用途产生了争议。本综述的目的是检查创伤复苏中 IO 导管的证据,并强调未来研究的领域。

方法

使用术语(“骨内通路”或“骨内通路”或“IO 通路”)对 1990 年 1 月至 2018 年 8 月发表的 PubMed 和 Embase 进行搜索,并进行了搜索。合格的原始文章描述了在一名或多名创伤患者的复苏中使用 IO 导管。排除了动物,尸体研究和涉及健康志愿者的研究。

结果

包括 9 项研究,共 1218 名创伤患者和 1432 次器械插入,成功率为 95%,并发症发生率为 0.9%。流量数据和溶血证据的报告很差。

结论

在创伤患者中,骨髓内导管具有较高的插入成功率和较低的并发症发生率。现有证据表明 IO 输血与溶血无关,但是需要对人类进行进一步的研究。在该人群中,通过 IO 导管输血的流量数据很少,尽管有很多轶事证据支持其使用。

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