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[大白鼠后肢再支配中坐骨神经和皮肤感受器结构与功能恢复的动态变化]

[Dynamics of the recovery of the structure and function of the sciatic nerve and skin receptors in reinnervation of the hindlimb of white rats].

作者信息

Chumasov E I, Enin L D, Svetnikova K M, Miroshnikova M E

出版信息

Biull Eksp Biol Med. 1988 Dec;106(12):728-32.

PMID:3207882
Abstract

The dynamics of the structural and functional repair of nerve trunks and receptor endings in the rat foot skin was studied on the model of sutureless connection of the damaged nerve by and implanted arterial vessel. Neurohistological and neurophysiological methods were used to show that the anatomical repair of the nerve integrity, maturation of nerve fibers and formation of receptor endings preceded their functional restoration. Terms of myelinization of regenerating axons, their diameters and initial stages of the formation of receptors in the foot skin were established. The restoration of the skin receptor function was shown to occur within 11-13 months after operation.

摘要

通过植入动脉血管对受损神经进行无缝连接的模型,研究了大鼠足部皮肤神经干和感受器末梢的结构与功能修复动态。采用神经组织学和神经生理学方法表明,神经完整性的解剖修复、神经纤维的成熟以及感受器末梢的形成先于其功能恢复。确定了再生轴突的髓鞘化条件、其直径以及足部皮肤感受器形成的初始阶段。结果表明,皮肤感受器功能的恢复在术后11 - 13个月内发生。

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