Sirotkin V V, Avtandilov G G, Volodin N D
Biull Eksp Biol Med. 1988 Dec;106(12):751-4.
The paper presents the results of studies of the influence of radiation on the sizes of cardiomyocyte mitochondria in rats. Considering the established regularity of subordination of mitochondrial size distribution to the gamma-law on the cardiomyocyte mitochondria, one can judge presumably on their functional state by the variation in the mitochondrial size distribution. This conclusion is confirmed by the relationship between the redistribution of mitochondrial size and the biochemical parameters of their functional activities. It is recommended to evaluate morphometrically the variation in mitochondrial sizes in the course of computer-assisted microscopic investigation of cells for the purpose of assessment of morphological and functional properties of these cellular organellae and the cell as a whole.
本文介绍了辐射对大鼠心肌细胞线粒体大小影响的研究结果。考虑到心肌细胞线粒体大小分布服从伽马定律这一既定规律，人们可以通过线粒体大小分布的变化推测其功能状态。线粒体大小的重新分布与其功能活动的生化参数之间的关系证实了这一结论。建议在对细胞进行计算机辅助显微镜检查过程中，从形态计量学角度评估线粒体大小的变化，以评估这些细胞器以及整个细胞的形态和功能特性。
