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[线粒体形态功能特性分布的双因素相关性分析]

[Dual-factor correlation analysis of the distribution of morphofunctional properties of mitochondria].

作者信息

Sirotkin V V, Grishin A Iu, Smirnov V A, Iurina N A, Lupichev L N

出版信息

Biull Eksp Biol Med. 1993 Feb;115(2):215-8.

PMID:8043814
Abstract

Judging by double-factorial correlative analysis of mitochondrial morpho-functional property distribution during the treatment of organism with radioactive rays, it has been established that there is a high correlation between mitochondrial dimensions in population and known structural-functional types. To detect the force and tightness of this parameters' connection, there lists a method of double-factorial correlative analysis. The value of correlation coefficient lets assume that mitochondrial functional activity depends on mitochondrial dimensions and is described by straight regression equation. It has been established that dimension's increase is accompanied by mitochondrial functional activity decrease and vice versa, though some functionally inactivated mitochondria can have little dimensions. Thus, knowing mitochondrial dimensions in population we can detect it's functional properties and detect mitochondrial dimensions knowing the functional properties by straight regression curves.

摘要

通过对机体进行放射性射线治疗期间线粒体形态功能特性分布的双因素相关分析可知,群体中线粒体尺寸与已知结构功能类型之间存在高度相关性。为检测这些参数联系的强度和紧密性,列出了一种双因素相关分析方法。相关系数的值表明线粒体功能活性取决于线粒体尺寸,并由线性回归方程描述。已确定尺寸增加伴随着线粒体功能活性降低,反之亦然,尽管一些功能失活的线粒体尺寸可能较小。因此,了解群体中线粒体的尺寸,我们可以通过线性回归曲线检测其功能特性,并且在知道功能特性时检测线粒体尺寸。

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