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Diagnostics (Basel). 2020 Feb 16;10(2):106. doi: 10.3390/diagnostics10020106.
2
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4
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J Womens Health (Larchmt). 2016 Mar;25(3):235-41. doi: 10.1089/jwh.2015.5735.
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Ups J Med Sci. 2018 Dec;123(4):225-229. doi: 10.1080/03009734.2018.1544597. Epub 2018 Dec 10.
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How relevant are ACOG and SGO guidelines for referral of adnexal mass?美国妇产科医师学会(ACOG)和妇科肿瘤学会(SGO)关于附件包块转诊的指南相关性如何?
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Ultrasound Obstet Gynecol. 2011 Oct;38(4):450-5. doi: 10.1002/uog.9012.

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Multi-modality deep learning model reaches high prediction accuracy in the diagnosis of ovarian cancer.多模态深度学习模型在卵巢癌诊断中达到高预测准确率。
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Mol Med Rep. 2021 Aug;24(2). doi: 10.3892/mmr.2021.12221. Epub 2021 Jun 16.
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A multidisciplinary approach remains the best strategy to improve and strengthen the management of ovarian cancer (Review).多学科方法仍然是改善和加强卵巢癌管理的最佳策略(综述)。
Int J Oncol. 2021 Jul;59(1). doi: 10.3892/ijo.2021.5233. Epub 2021 Jun 16.

本文引用的文献

1
O-RADS US Risk Stratification and Management System: A Consensus Guideline from the ACR Ovarian-Adnexal Reporting and Data System Committee.O-RADS US 风险分层与管理系统:ACR 卵巢-附件报告和数据系统委员会的共识指南。
Radiology. 2020 Jan;294(1):168-185. doi: 10.1148/radiol.2019191150. Epub 2019 Nov 5.
2
ACR Appropriateness Criteria Clinically Suspected Adnexal Mass, No Acute Symptoms.美国放射学会适宜性标准:临床怀疑附件包块,无急性症状
J Am Coll Radiol. 2019 May;16(5S):S77-S93. doi: 10.1016/j.jacr.2019.02.011.
3
Risk of complications in patients with conservatively managed ovarian tumours (IOTA5): a 2-year interim analysis of a multicentre, prospective, cohort study.保守治疗的卵巢肿瘤患者的并发症风险(IOTA5):一项多中心、前瞻性队列研究的 2 年中期分析。
Lancet Oncol. 2019 Mar;20(3):448-458. doi: 10.1016/S1470-2045(18)30837-4. Epub 2019 Feb 5.
4
Comparison of Longitudinal CA125 Algorithms as a First-Line Screen for Ovarian Cancer in the General Population.普通人群中作为一线筛查的纵向 CA125 算法比较。
Clin Cancer Res. 2018 Oct 1;24(19):4726-4733. doi: 10.1158/1078-0432.CCR-18-0208. Epub 2018 Jul 3.
5
Comparison of two protocols for the management of asymptomatic postmenopausal women with adnexal tumours - a randomised controlled trial of RMI/RCOG vs Simple Rules.两种管理无症状绝经后附件肿瘤女性方案的比较——RMI/RCOG与简单规则的随机对照试验
Br J Cancer. 2017 Feb 28;116(5):584-591. doi: 10.1038/bjc.2017.17. Epub 2017 Feb 2.
6
Subjective assessment versus ultrasound models to diagnose ovarian cancer: A systematic review and meta-analysis.主观评估与超声模型诊断卵巢癌:一项系统评价与荟萃分析
Eur J Cancer. 2016 May;58:17-29. doi: 10.1016/j.ejca.2016.01.007. Epub 2016 Feb 27.
7
Comparing the Copenhagen Index (CPH-I) and Risk of Ovarian Malignancy Algorithm (ROMA): Two equivalent ways to differentiate malignant from benign ovarian tumors before surgery?比较哥本哈根指数(CPH-I)和卵巢恶性肿瘤风险算法(ROMA):在手术前区分良恶性卵巢肿瘤的两种等效方法?
Gynecol Oncol. 2016 Mar;140(3):481-5. doi: 10.1016/j.ygyno.2016.01.023. Epub 2016 Jan 26.
8
Are serum HE4 or ROMA scores useful to experienced examiners for improving characterization of adnexal masses after transvaginal ultrasonography?血清 HE4 或 ROMA 评分是否有助于有经验的检查者在经阴道超声检查后改善附件肿块的特征化?
Ultrasound Obstet Gynecol. 2014 Jan;43(1):89-97. doi: 10.1002/uog.12551. Epub 2013 Dec 4.
9
Subjective assessment by ultrasound is superior to the risk of malignancy index (RMI) or the risk of ovarian malignancy algorithm (ROMA) in discriminating benign from malignant adnexal masses.超声主观评估优于肿瘤恶性风险指数(RMI)或卵巢恶性肿瘤算法(ROMA),可用于鉴别附件良恶性肿块。
Eur J Cancer. 2012 Jul;48(11):1649-56. doi: 10.1016/j.ejca.2011.12.003. Epub 2012 Jan 5.
10
How relevant are ACOG and SGO guidelines for referral of adnexal mass?美国妇产科医师学会(ACOG)和妇科肿瘤学会(SGO)关于附件包块转诊的指南相关性如何?
Obstet Gynecol. 2007 Oct;110(4):841-8. doi: 10.1097/01.AOG.0000267198.25223.bc.

基于卵巢肿物临床表现转诊至妇科肿瘤学家的准确性。

Accuracy in Referrals to Gynecologic Oncologists Based on Clinical Presentation for Ovarian Mass.

作者信息

Chua Katherine Jane C, Patel Ricky D, Trivedi Radhika, Greenberg Patricia, Beiter Kyle, Magliaro Thomas, Patel Ushma, Varughese Joyce

机构信息

Department of Obstetrics and Gynecology, Saint Peter's University Hospital, New Brunswick, NJ 08901, USA.

Biostatistics and Epidemiology Services Center, Rutgers School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.

出版信息

Diagnostics (Basel). 2020 Feb 16;10(2):106. doi: 10.3390/diagnostics10020106.

DOI:10.3390/diagnostics10020106
PMID:32079078
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7168930/
Abstract

Ovarian cancer is one of the most lethal gynecological cancers in women due to late diagnosis. Despite technological advancements, experienced physicians have high sensitivities and specificities in subjective assessments when combining ultrasound findings and clinical history in analyzing adnexal masses. This study aims to demonstrate general obstetricians and gynecologists' (OB/GYN) appropriateness in gynecologic oncologist referrals for malignant ovarian masses based on history and physical (H&P), imaging, and available tumor markers. Three board certified OB/GYNs were given 148 cases and determined whether or not they would refer them to a gynecologic oncologist. Results showed that OB/GYNs were 81-85% accurate in diagnosing patients with a benign or malignant disease. Among the malignant cases, reviewers had a high sensitivity ranging from 74-81% in appropriately referring a malignancy. In our study, OB/GYNs referred between 23-32% of ovarian masses to a gynecologic oncologist with only 9.5% of cases found to be malignant. Despite the high referral rates, generalists showed a high degree of sensitivity in accurately referring malignant diseases based solely on clinical experience and imaging studies, which could improve survival rates with early intervention by gynecologic oncologists.

摘要

由于诊断较晚,卵巢癌是女性最致命的妇科癌症之一。尽管技术不断进步,但经验丰富的医生在结合超声检查结果和临床病史分析附件包块时,主观评估具有较高的敏感性和特异性。本研究旨在基于病史和体格检查(H&P)、影像学检查以及可用的肿瘤标志物,证明普通妇产科医生(OB/GYN)将恶性卵巢包块转诊给妇科肿瘤学家的合理性。三位获得委员会认证的妇产科医生收到了148个病例,并确定是否会将这些病例转诊给妇科肿瘤学家。结果显示,妇产科医生在诊断良性或恶性疾病患者方面的准确率为81%-85%。在恶性病例中,评审人员在正确转诊恶性肿瘤方面的敏感性较高,范围为74%-81%。在我们的研究中,妇产科医生将23%-32%的卵巢包块转诊给了妇科肿瘤学家,其中只有9.5%的病例被发现为恶性。尽管转诊率较高,但通科医生仅根据临床经验和影像学研究在准确转诊恶性疾病方面表现出了较高的敏感性,这可以通过妇科肿瘤学家的早期干预提高生存率。