Chua Katherine Jane C, Patel Ricky D, Trivedi Radhika, Greenberg Patricia, Beiter Kyle, Magliaro Thomas, Patel Ushma, Varughese Joyce
Department of Obstetrics and Gynecology, Saint Peter's University Hospital, New Brunswick, NJ 08901, USA.
Biostatistics and Epidemiology Services Center, Rutgers School of Public Health, Rutgers University, Piscataway, NJ 08854, USA.
Diagnostics (Basel). 2020 Feb 16;10(2):106. doi: 10.3390/diagnostics10020106.
Ovarian cancer is one of the most lethal gynecological cancers in women due to late diagnosis. Despite technological advancements, experienced physicians have high sensitivities and specificities in subjective assessments when combining ultrasound findings and clinical history in analyzing adnexal masses. This study aims to demonstrate general obstetricians and gynecologists' (OB/GYN) appropriateness in gynecologic oncologist referrals for malignant ovarian masses based on history and physical (H&P), imaging, and available tumor markers. Three board certified OB/GYNs were given 148 cases and determined whether or not they would refer them to a gynecologic oncologist. Results showed that OB/GYNs were 81-85% accurate in diagnosing patients with a benign or malignant disease. Among the malignant cases, reviewers had a high sensitivity ranging from 74-81% in appropriately referring a malignancy. In our study, OB/GYNs referred between 23-32% of ovarian masses to a gynecologic oncologist with only 9.5% of cases found to be malignant. Despite the high referral rates, generalists showed a high degree of sensitivity in accurately referring malignant diseases based solely on clinical experience and imaging studies, which could improve survival rates with early intervention by gynecologic oncologists.
由于诊断较晚,卵巢癌是女性最致命的妇科癌症之一。尽管技术不断进步,但经验丰富的医生在结合超声检查结果和临床病史分析附件包块时,主观评估具有较高的敏感性和特异性。本研究旨在基于病史和体格检查(H&P)、影像学检查以及可用的肿瘤标志物,证明普通妇产科医生(OB/GYN)将恶性卵巢包块转诊给妇科肿瘤学家的合理性。三位获得委员会认证的妇产科医生收到了148个病例,并确定是否会将这些病例转诊给妇科肿瘤学家。结果显示,妇产科医生在诊断良性或恶性疾病患者方面的准确率为81%-85%。在恶性病例中,评审人员在正确转诊恶性肿瘤方面的敏感性较高,范围为74%-81%。在我们的研究中,妇产科医生将23%-32%的卵巢包块转诊给了妇科肿瘤学家,其中只有9.5%的病例被发现为恶性。尽管转诊率较高,但通科医生仅根据临床经验和影像学研究在准确转诊恶性疾病方面表现出了较高的敏感性,这可以通过妇科肿瘤学家的早期干预提高生存率。