From the Section of Dermatology, Department of Surgery, Dartmouth-Hitchcock Medical Center, Lebanon, NH.
Department of Epidemiology, Geisel School of Medicine at Dartmouth, Hanover, NH.
Epidemiology. 2020 May;31(3):448-450. doi: 10.1097/EDE.0000000000001179.
Cosmetic tattoos use dyes with carcinogenic potential. Skin cancers arising in tattoos have been reported.
We investigated whether risk of early onset basal cell carcinoma was related to the site and colors of cosmetic tattoos as part of a population-based case-control study of cases (ages 25-50 years), identified from a state-wide surveillance system, and age- and gender-matched controls, selected from driver's license records, randomly assigned an anatomic site of the cases.
One hundred fifty-six cases (17%) with early onset basal cell carcinoma and 213 controls (26%) reported cosmetic tattoos. Among those with tattoos, the adjusted odds ratio of basal cell carcinoma at the tattoo site compared to another site was 1.8 (95% confidence interval = 1.0, 3.2). We observed the strongest associations for yellow and green tattoo colors.
Our preliminary findings support the possibility of an enhanced risk of early onset basal cell carcinomas at the site of cosmetic tattoos.
美容纹身使用具有致癌潜力的染料。已有报告称纹身部位会出现皮肤癌。
我们通过一项基于人群的病例对照研究来调查早期基底细胞癌的发病风险是否与美容纹身的部位和颜色有关，该研究中的病例（年龄 25-50 岁）是从全州监测系统中确定的，年龄和性别匹配的对照是从驾驶执照记录中随机选择的，对照被分配到病例的解剖部位。
156 例（17%）早期基底细胞癌患者和 213 例对照（26%）报告有美容纹身。在有纹身的人群中，与其他部位相比，纹身部位基底细胞癌的调整比值比为 1.8（95%置信区间=1.0，3.2）。我们观察到黄色和绿色纹身颜色与基底细胞癌的相关性最强。
我们的初步发现支持美容纹身部位发生早期基底细胞癌风险增加的可能性。
