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创伤和分离对暴食障碍认知行为治疗结果的影响:一项 6 个月的前瞻性研究。

The effect of trauma and dissociation on the outcome of cognitive behavioural therapy for binge eating disorder: A 6-month prospective study.

机构信息

Department of Human Neurosciences and Mental Health, Sapienza University of Rome, Rome, Italy.

Research Group Psychiatry, Department of Neurosciences, KU Leuven University, Leuven, Belgium.

出版信息

Eur Eat Disord Rev. 2020 May;28(3):309-317. doi: 10.1002/erv.2722. Epub 2020 Feb 20.

Abstract

BACKGROUND

Binge eating disorder (BED) is commonly associated with a history of trauma. Yet, there is little insight into the potential effect that trauma, dissociation, and depressive symptoms may have on the outcome of treatment interventions.

METHODS

A total of 142 treatment-seeking patients admitted with a diagnosis of DSM-5 BED (88% female; mean age = 38.7; SD = 10.8) took part in a 6-month, protocolized, group cognitive behavioural therapy (CBT). Self-report questionnaires were administered to assess lifetime traumatic experiences, dissociation, and depression. Body mass index and the number of binges per week (BPW) were measured throughout treatment. The main outcomes were the percentage reduction in BPW and remission (i.e., less than one BPW; cf. DSM-5).

RESULTS

Most BED patients (91.5%) reported a history of trauma, with two in three patients reporting three or more traumatic experiences. Whereas the number of traumatic experiences was not significantly associated with a reduction in BPW or remission, a higher traumatic impact score significantly decreased the likelihood of obtaining remission at the end of treatment (OR = 0.96; 95% CI [0.92, 0.99]). Higher levels of dissociative symptoms partially mediated this prospective association.

CONCLUSIONS

The impact of traumatic experiences, as opposed to the number of traumatic experiences experienced, negatively predicts remission after 6 months of CBT. These findings highlight the importance of addressing trauma and dissociative features in the CBT treatment of BED.

摘要

背景

暴食障碍(BED)通常与创伤史有关。然而,对于创伤、分离和抑郁症状可能对治疗干预结果的潜在影响,我们知之甚少。

方法

共有 142 名符合 DSM-5 BED 诊断标准的治疗性就诊患者(88%为女性;平均年龄=38.7;SD=10.8)参加了为期 6 个月的程序化团体认知行为治疗(CBT)。使用自我报告问卷评估终生创伤经历、分离和抑郁。在整个治疗过程中测量体重指数和每周暴食次数(BPW)。主要结果是 BPW 的百分比减少和缓解(即,少于一次 BPW;参照 DSM-5)。

结果

大多数 BED 患者(91.5%)报告有创伤史,三分之二的患者报告有 3 次或更多的创伤经历。尽管创伤经历的数量与 BPW 的减少或缓解无关,但较高的创伤影响评分显著降低了治疗结束时获得缓解的可能性(OR=0.96;95%CI[0.92,0.99])。较高水平的分离症状部分中介了这种前瞻性关联。

结论

与经历的创伤数量相比,创伤经历的影响负性预测了 CBT 治疗 6 个月后的缓解。这些发现强调了在 BED 的 CBT 治疗中解决创伤和分离特征的重要性。

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