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宫腔镜治疗原发性子宫内膜边缘区B细胞淋巴瘤(黏膜相关淋巴组织淋巴瘤)

Hysteroscopic Treatment of Primary Endometrial Marginal Zone B-cell Lymphoma (MALToma).

作者信息

Scrimin F, Magoga G, Di Lorenzo G, Romano F, De Angelis M C, Vitagliano A, Crugno J, Di Spiezio Sardo A

机构信息

Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste, Italy.

Istituto di Ginecologia e Obstetricia, Università Cattolica del Sacro Cuore, Rome, Italy.

出版信息

Facts Views Vis Obgyn. 2019 Sep;11(3):257-260.

PMID:32082533
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7020950/
Abstract

Primary extranodal marginal zone B-cell lymphomas (MALToma) of the endometrium are rare tumors. We report a case of MALToma diagnosed within an endometrial polyp in a patient presenting with postmenopausal vaginal bleeding. The patient underwent a conventional hysteroscopic procedure for intrauterine polyps. There was no suspicion of malignancy during the preoperative investigations or at surgery. Conventional bipolar resection of the polyps was performed. The present case demonstrates that conservative management of endometrial MALToma may be considered as a safe alternative to hysterectomy. Further data on long-term follow up is needed to confirm the safety of this conservative approach.

摘要

子宫内膜原发性结外边缘区B细胞淋巴瘤(黏膜相关淋巴组织淋巴瘤)是罕见肿瘤。我们报告1例在出现绝经后阴道出血的患者子宫内膜息肉内诊断出的黏膜相关淋巴组织淋巴瘤病例。该患者因子宫内息肉接受了传统宫腔镜手术。术前检查或手术时均未怀疑有恶性肿瘤。对息肉进行了传统双极切除术。本病例表明,子宫内膜黏膜相关淋巴组织淋巴瘤的保守治疗可被视为子宫切除术的一种安全替代方案。需要更多长期随访数据来证实这种保守方法的安全性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9e/7020950/e676d092cabc/FVVinObGyn-11-257-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9e/7020950/ca07a78089e7/FVVinObGyn-11-257-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9e/7020950/67f8e8889e04/FVVinObGyn-11-257-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9e/7020950/e676d092cabc/FVVinObGyn-11-257-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9e/7020950/ca07a78089e7/FVVinObGyn-11-257-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9e/7020950/67f8e8889e04/FVVinObGyn-11-257-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fe9e/7020950/e676d092cabc/FVVinObGyn-11-257-g003.jpg

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1
Hysteroscopic Treatment of Primary Endometrial Marginal Zone B-cell Lymphoma (MALToma).宫腔镜治疗原发性子宫内膜边缘区B细胞淋巴瘤(黏膜相关淋巴组织淋巴瘤)
Facts Views Vis Obgyn. 2019 Sep;11(3):257-260.
2
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PLoS One. 2015 Dec 11;10(12):e0144857. doi: 10.1371/journal.pone.0144857. eCollection 2015.
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Endometrial marginal zone B-cell MALT-type lymphoma: case report and literature review.子宫内膜边缘区 B 细胞黏膜相关淋巴组织型淋巴瘤:病例报告及文献复习。
Crit Rev Oncol Hematol. 2013 Nov;88(2):246-52. doi: 10.1016/j.critrevonc.2013.05.016. Epub 2013 Jun 28.

本文引用的文献

1
Effectiveness of Hysteroscopic Techniques for Endometrial Polyp Removal: The Italian Multicenter Trial.宫腔镜技术治疗子宫内膜息肉的有效性:意大利多中心试验。
J Minim Invasive Gynecol. 2019 Sep-Oct;26(6):1169-1176. doi: 10.1016/j.jmig.2018.12.002. Epub 2018 Dec 7.
2
Overview on the management of non-gastric MALT lymphomas.非胃黏膜相关淋巴组织淋巴瘤的管理概述
Best Pract Res Clin Haematol. 2018 Mar;31(1):57-64. doi: 10.1016/j.beha.2017.11.001. Epub 2017 Nov 14.
3
A Polypectomy Nearly Becoming a Tragedy: A Case of Multiorgan Perforation.
一例险些酿成悲剧的息肉切除术:多器官穿孔病例
J Minim Invasive Gynecol. 2018 Jul-Aug;25(5):763-764. doi: 10.1016/j.jmig.2018.01.006. Epub 2018 Jan 12.
4
Primary extranodal marginal zone B cell lymphoma of the uterus: a case study and review of the literature.子宫原发性结外边缘区B细胞淋巴瘤:一例病例报告及文献复习
J Clin Pathol. 2014 Apr;67(4):375-7. doi: 10.1136/jclinpath-2013-202059. Epub 2013 Dec 18.
5
Endometrial marginal zone B-cell MALT-type lymphoma: case report and literature review.子宫内膜边缘区 B 细胞黏膜相关淋巴组织型淋巴瘤:病例报告及文献复习。
Crit Rev Oncol Hematol. 2013 Nov;88(2):246-52. doi: 10.1016/j.critrevonc.2013.05.016. Epub 2013 Jun 28.
6
Primary uterine localization of malt lymphoma: a case report and literature review.
Leuk Res. 2011 Nov;35(11):e185-7. doi: 10.1016/j.leukres.2011.07.003. Epub 2011 Jul 28.
7
A case of primary MALT lymphoma of the endometrium presenting as an asymptomatic polyp.一例表现为无症状息肉的子宫内膜原发性黏膜相关淋巴组织淋巴瘤。
Ann Hematol. 2009 May;88(5):491-3. doi: 10.1007/s00277-008-0615-4. Epub 2008 Oct 11.
8
Extranodal lymphoma: a reappraisal.结外淋巴瘤:重新评估
Ann Oncol. 2008 Jun;19 Suppl 4:iv77-80. doi: 10.1093/annonc/mdn204.
9
Lymphomas of the female genital tract: a study of 186 cases and review of the literature.女性生殖道淋巴瘤:186例病例研究及文献综述
Am J Surg Pathol. 2005 Nov;29(11):1512-20. doi: 10.1097/01.pas.0000178089.77018.a9.