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原发性心脏肿瘤手术切除的早期和晚期结果:我们单机构的经验。

Early and late results in surgical excision of primary cardiac tumors: Our single-institution experience.

作者信息

Kuplay Hüseyin, Kurç Erol, Mete Evren Müge, Kuş Zuhal, Bayer Erdoğan Sevinç, Akansel Serdar, Tandoğar Selçuk Nehir, Aykut Aka Serap

机构信息

Department of Cardiovascular Surgery, Dr. Siyami Ersek Thoracic and Cardiovascular Surgery Training and Research Hospital, İstanbul, Turkey.

Department of Pathology, Haydarpasa Numune Training and Research Hospital, İstanbul, Turkey.

出版信息

Turk Gogus Kalp Damar Cerrahisi Derg. 2018 Apr 30;26(2):177-182. doi: 10.5606/tgkdc.dergisi.2018.14985. eCollection 2018 Apr.

Abstract

BACKGROUND

In the present study, we present our experience for surgical excision for cardiac masses and to analyze survival characteristics of these patients.

METHODS

Between January 2004 and December 2015, a total of 131 patients (88 females, 43 males; mean age 49.4±16.2 years; range, 1.2 months to 81 years) with primary cardiac tumors who underwent surgery in our center were included in this study. Demographic and other patient-related data were retrospectively reviewed from medical records of our center.

RESULTS

All benign tumors were completely resected, whereas only palliative procedures were performed for malignant tumors. Pathology results revealed 88.5% (n=116) benign and 11.5% (n=15) malignant tumors. Tumors were most frequently located in the left atrium (76.3%, n=100), followed by the right atrium (11.5%, n=15), and the right ventricle (5.3%, n=7). Among all patients, 116 (88.5%) survived, while late mortality was seen in 15 patients (11.5%). The mean survival was 130.6±4.5 months. The latest mortality was observed at 124 months, whereby the cumulative survival rate was 79.2%. There was a statistically significant relationship between mortality and pathological characteristics of the tumor, and malignant cases had significantly higher mortality rates (p=0.002).

CONCLUSION

Surgical resection of primary cardiac tumors can be performed with low morbidity and mortality rates. Although survival rates in benign tumors are satisfactory, patients with malignant tumors have poor prognosis. The main clinical predic.

摘要

背景

在本研究中,我们介绍了心脏肿物手术切除的经验,并分析了这些患者的生存特征。

方法

2004年1月至2015年12月期间,本中心共有131例原发性心脏肿瘤患者(88例女性,43例男性;平均年龄49.4±16.2岁;范围为1.2个月至81岁)接受了手术,纳入本研究。从本中心的病历中回顾性地查阅了人口统计学和其他患者相关数据。

结果

所有良性肿瘤均被完全切除,而恶性肿瘤仅进行了姑息性手术。病理结果显示良性肿瘤占88.5%(n=116),恶性肿瘤占11.5%(n=15)。肿瘤最常位于左心房(76.3%,n=100),其次是右心房(11.5%,n=15)和右心室(5.3%,n=7)。所有患者中,116例(88.5%)存活,15例(11.5%)出现晚期死亡。平均生存期为130.6±4.5个月。最晚死亡发生在124个月,累积生存率为79.2%。死亡率与肿瘤的病理特征之间存在统计学显著关系,恶性病例的死亡率明显更高(p=0.002)。

结论

原发性心脏肿瘤的手术切除可以在低发病率和死亡率的情况下进行。虽然良性肿瘤的生存率令人满意,但恶性肿瘤患者的预后较差。主要临床预测……

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