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小儿心脏手术中的罕见手术:儿童心脏肿瘤

Rare operations in pediatric heart surgery: Cardiac tumors in childhood.

作者信息

Koç Murat, Kutsal Ali

机构信息

Department of Cardiovascular Surgery, Dr. Sami Ulus Maternity and Children?s Training and Research Hospital, Ankara, Turkey.

出版信息

Turk Gogus Kalp Damar Cerrahisi Derg. 2018 Sep 16;26(4):544-549. doi: 10.5606/tgkdc.dergisi.2018.16147. eCollection 2018 Oct.

DOI:10.5606/tgkdc.dergisi.2018.16147
PMID:32082795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7018197/
Abstract

BACKGROUND

In this study, we present our 12-year experience in the surgical treatment of primary cardiac tumors in childhood.

METHODS

Thirteen pediatric patients (8 males, 5 females; mean age 1.3±1.9 years; range, 3 days to 6 years) who were operated for a primary cardiac tumor in our center between January 2005 and December 2017 were included in this study. The data were evaluated retrospectively based on our medical records.

RESULTS

All of the masses resected were benign. However, the most common tumor was rhabdomyoma (n=7), followed by fibroma (n=3), myxoma (n=2), and pericardial teratoma (n=1). The mortality rate was 15.4%, as two patients died in the early postoperative period. No residual mass or tumor recurrence was observed in the early and late postoperative period in the remaining patients.

CONCLUSION

Although primary cardiac tumors in childhood are usually benign, they may cause clinically significant problems depending on the localization and size of the tumor. Surgical tumor excision is often associated with good long-term outcomes.

摘要

背景

在本研究中,我们介绍了我们在儿童原发性心脏肿瘤手术治疗方面的12年经验。

方法

本研究纳入了2005年1月至2017年12月期间在我们中心接受原发性心脏肿瘤手术的13例儿科患者(8例男性,5例女性;平均年龄1.3±1.9岁;范围为3天至6岁)。基于我们的病历对数据进行回顾性评估。

结果

所有切除的肿块均为良性。然而,最常见的肿瘤是横纹肌瘤(n = 7),其次是纤维瘤(n = 3)、黏液瘤(n = 2)和心包畸胎瘤(n = 1)。死亡率为15.4%,因为有2例患者在术后早期死亡。其余患者在术后早期和晚期均未观察到残留肿块或肿瘤复发。

结论

尽管儿童原发性心脏肿瘤通常为良性,但根据肿瘤的位置和大小,它们可能会引起临床上的重大问题。手术切除肿瘤通常会带来良好的长期效果。

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本文引用的文献

1
Early and late results in surgical excision of primary cardiac tumors: Our single-institution experience.原发性心脏肿瘤手术切除的早期和晚期结果:我们单机构的经验。
Turk Gogus Kalp Damar Cerrahisi Derg. 2018 Apr 30;26(2):177-182. doi: 10.5606/tgkdc.dergisi.2018.14985. eCollection 2018 Apr.
2
MR imaging of cardiac tumors and masses: a review of methods and clinical applications.心脏肿瘤和肿块的磁共振成像:方法和临床应用综述。
Radiology. 2013 Jul;268(1):26-43. doi: 10.1148/radiol.13121239.
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Primary cardiac tumors: 32 years of experience from a Spanish tertiary surgical center.原发性心脏肿瘤:西班牙三级外科中心 32 年的经验。
Cardiovasc Pathol. 2013 Nov-Dec;22(6):424-7. doi: 10.1016/j.carpath.2013.04.006. Epub 2013 May 30.
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Cardiac tumors in infants and children: study of 120 operated patients.婴幼儿心脏肿瘤:120例手术患者的研究
Pediatr Cardiol. 2013 Jan;34(1):125-8. doi: 10.1007/s00246-012-0399-0. Epub 2012 Jun 27.
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Cardiac tumors and associated arrhythmias in pediatric patients, with observations on surgical therapy for ventricular tachycardia.儿科患者的心脏肿瘤和相关心律失常,以及对室性心动过速的手术治疗观察。
J Am Coll Cardiol. 2011 Oct 25;58(18):1903-9. doi: 10.1016/j.jacc.2011.08.005.
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Cardiac tumours: diagnosis and management.心脏肿瘤:诊断与管理
Heart. 2011 Jan;97(2):151-60. doi: 10.1136/hrt.2009.186320.
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Vasoactive-inotropic score as a predictor of morbidity and mortality in infants after cardiopulmonary bypass.血管活性-正性肌力评分预测体外循环后婴儿的发病率和死亡率。
Pediatr Crit Care Med. 2010 Mar;11(2):234-8. doi: 10.1097/PCC.0b013e3181b806fc.
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Pathological study of primary cardiac and pericardial tumours in a specialist UK Centre: surgical and autopsy series.英国一家专业中心原发性心脏和心包肿瘤的病理学研究:外科和尸检系列。
Cardiovasc Pathol. 2010 Nov-Dec;19(6):343-52. doi: 10.1016/j.carpath.2009.07.005. Epub 2009 Sep 10.
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Clinical analysis and surgical results of cardiac myxoma in pediatric patients.小儿心脏黏液瘤的临床分析与手术结果
J Surg Oncol. 2009 Jan 1;99(1):48-50. doi: 10.1002/jso.21175.
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Treatment strategies for pediatric patients with primary cardiac and pericardial tumors: a 30-year review.小儿原发性心脏和心包肿瘤的治疗策略:一项30年的回顾。
Pediatr Cardiol. 2008 Nov;29(6):1071-6. doi: 10.1007/s00246-008-9256-6. Epub 2008 Jul 4.