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心脏黏液瘤的手术治疗:单中心经验

Operative management of intracardiac myxomas: A single center experience.

作者信息

Mishra Amit, Shah Mehul, Sharma Pranav, Kothari Jignesh, Malhotra Amber

机构信息

Associate Professor, Pediatric Cardiac Surgery, Department of Cardiovascular and Thoracic Surgery, U.N. Mehta Institute of Cardiology and Research Center, Asarwa, Ahmedabad 380016, Gujarat, India.

Associate Professor, Department of Cardiovascular and Thoracic Surgery, U.N. Mehta Institute of Cardiology and Research Center, Ahmedabad, Gujarat, India.

出版信息

Med J Armed Forces India. 2014 Jan;70(1):5-9. doi: 10.1016/j.mjafi.2013.05.009. Epub 2013 Aug 30.

DOI:10.1016/j.mjafi.2013.05.009
PMID:24623939
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3946407/
Abstract

BACKGROUND

Cardiac myxomas are the most common benign intracardiac tumors. We studied the clinical presentation of cardiac myxomas, their morbidity, mortality and recurrence rate following surgery at our institution over a period of four years.

METHODS

During August 2008 to November 2012, a total of 12023 cardiac surgeries were performed. Amongst these, 50 patients (12 males, 38 females) underwent complete removal of primary or recurrent intracardiac myxomas. Complete tumor excision with a cuff of interatrial septum followed copious saline irrigation of the cardiac chambers was performed in each case.

RESULTS

Forty six patients survived the surgery of which 43 are being followed up at regular intervals for development of recurrence. Myxomas constituted 0.41% of the total cardiac surgeries at our institute. Most of them were noted in the fourth decade. The commonest location was left atrium (74%) followed by right atrium (22%). Only one patient had a myxoma in the right ventricle. Forty six patients (92%) survived the surgery.

CONCLUSION

Cardiac myxoma excision account for a very small percentage of cardiac procedures. Immediate surgical treatment is indicated in all patients. Cardiac myxomas can be excised with a low rate of mortality and morbidity.

摘要

背景

心脏黏液瘤是最常见的心脏良性肿瘤。我们研究了心脏黏液瘤的临床表现、在我院四年期间手术后的发病率、死亡率和复发率。

方法

2008年8月至2012年11月期间,共进行了12023例心脏手术。其中,50例患者(12例男性,38例女性)接受了原发性或复发性心脏黏液瘤的完整切除。每例均在完整切除肿瘤并带有房间隔袖口后,用大量生理盐水冲洗心腔。

结果

46例患者手术后存活,其中43例定期接受随访以观察复发情况。黏液瘤占我院心脏手术总数的0.41%。大多数患者发病于第四个十年。最常见的部位是左心房(74%),其次是右心房(22%)。只有1例患者的黏液瘤位于右心室。46例患者(92%)手术后存活。

结论

心脏黏液瘤切除术在心脏手术中所占比例非常小。所有患者均应立即进行手术治疗。心脏黏液瘤切除手术的死亡率和发病率较低。

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Cardiac myxomas: 24 years of experience in 49 patients.心脏黏液瘤:49例患者的24年经验
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The role of interleukin-6 in cases of cardiac myxoma. Clinical features, immunologic abnormalities, and a possible role in recurrence.白细胞介素-6在心脏黏液瘤病例中的作用。临床特征、免疫异常及在复发中的可能作用。
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Cardiac myxoma: 40 years' experience in 63 patients.心脏黏液瘤:63例患者的40年经验
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J Cardiovasc Surg (Torino). 1993 Feb;34(1):49-53.
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Atrial myxoma: national incidence, diagnosis and surgical management.心房黏液瘤:全国发病率、诊断与外科治疗
Ir J Med Sci. 1993 Jun;162(6):223-6. doi: 10.1007/BF02945200.
10
Familial cardiac myxoma. A study of relatives of patients with myxoma.家族性心脏黏液瘤。对黏液瘤患者亲属的一项研究。
Chest. 1994 Jan;105(1):65-8. doi: 10.1378/chest.105.1.65.