Department of Psychology, Umeå University, Umeå, Sweden.
Centre for Demographic and Ageing Research (CEDAR), Umeå University, Umeå, Sweden.
J Alzheimers Dis. 2020;74(3):735-740. doi: 10.3233/JAD-190920.
High mental demands at work was examined as a possible protective factor to reduce the risk of dementia in 1,277 initially dementia-free participants, aged 60 years and older. The cohort was followed for a mean of 13.6 years. During follow-up, 376 participants developed all-cause dementia (Alzheimer's disease = 199; vascular dementia = 145). The association between mental demands at work and dementia was analyzed with Cox hazard models, adjusted for a range of covariates. The results revealed no significant association between mental demands at work and incidence of dementia. Based on the measures used in this study, it was concluded that high mental demands at work may not reduce the risk of dementia later in life.
本研究旨在探讨工作中的高心理需求是否为保护因素，以降低 1277 名年龄在 60 岁及以上、最初无痴呆的参与者发生痴呆的风险。该队列的平均随访时间为 13.6 年。随访期间，376 名参与者发生了全因痴呆（阿尔茨海默病=199；血管性痴呆=145）。采用 Cox 风险模型分析了工作中的心理需求与痴呆之间的关系，并对一系列协变量进行了调整。结果显示，工作中的心理需求与痴呆的发生无显著相关性。基于本研究中使用的测量方法，得出的结论是，工作中的高心理需求可能不会降低晚年发生痴呆的风险。
