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神经心理学与痴呆谱系:鉴别诊断、临床管理及法医应用

Neuropsychology and the dementia spectrum: Differential diagnosis, clinical management, and forensic utility.

作者信息

Begali Vivian L

机构信息

Neuropsychology and Psychological Healthcare, Fountain Park Medical Offices, 9327 MidlothianTurnpike, Suite 1-C, Richmond, VA 23235, USA Tel.: +1 804 728 2964; E-mail:

出版信息

NeuroRehabilitation. 2020;46(2):181-194. doi: 10.3233/NRE-192965.

DOI:10.3233/NRE-192965
PMID:32083596
Abstract

BACKGROUND

The utility of neuropsychology in the treatment and evaluation of neuropsychological disorders and neurodegenerative diseases is supported by scientific study. As a discipline, neuropsychology's value and efficacy when applied to the dementia spectrum are rooted in its inherent adaptability as a practical, cost-effective, and scientifically based resource for differential diagnosis, treatment planning, and forensic decision making.

OBJECTIVES

This article provides a framework for conceptualizing dementia as a spectrum of disorders and outlines a rationale for preferential reliance upon neuropsychological tenets. The function of neuropsychology in differential diagnosis, clinical management, integrative care, and forensic applications is delineated for use as a contemporary interdisciplinary reference.

METHODOLOGY

An overview of the literature on dementia as a spectrum of disorders has been integrated with the science and practice of neuropsychology.

CONCLUSIONS

The utility of neuropsychology emanates from its focus on brain functioning and the discipline's appreciation for the relationship between brain functioning and cognition, mental state, and behavior. Early and routine referral for neuropsychological assessment allows for the objective determination of normal versus abnormal neurocognitive functioning, provides a baseline for serial reassessment, and leads to the more rapid deployment of effective treatments. Beyond the hospital and clinic, neuropsychological expertise is increasingly sought after as integral to the legal system when decisions regarding eligibility for long term care and questions about capacity require objective and reliable measurement.

摘要

背景

科学研究支持神经心理学在神经心理障碍和神经退行性疾病的治疗与评估中的作用。作为一门学科,神经心理学应用于痴呆谱系时的价值和功效源于其固有的适应性,它是一种实用、具有成本效益且基于科学的资源,可用于鉴别诊断、治疗规划和法医决策。

目的

本文提供了一个将痴呆概念化为一系列障碍的框架,并概述了优先依赖神经心理学原则的基本原理。阐述了神经心理学在鉴别诊断、临床管理、综合护理和法医应用中的作用,以供当代跨学科参考。

方法

将关于痴呆作为一系列障碍的文献综述与神经心理学的科学和实践相结合。

结论

神经心理学的效用源于其对脑功能的关注以及该学科对脑功能与认知、精神状态和行为之间关系的认识。早期和常规转诊进行神经心理学评估有助于客观确定神经认知功能正常与否,为系列重新评估提供基线,并能更快地部署有效治疗。在医院和诊所之外,当涉及长期护理资格的决策以及能力问题需要客观可靠的衡量时,神经心理学专业知识作为法律系统不可或缺的一部分,需求日益增加。

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