Li Chris J, Yaghy Antonio, Shields Carol L
Ophthalmic Surg Lasers Imaging Retina. 2020 Feb 1;51(2):124. doi: 10.3928/23258160-20200129-10.
A 36-year-old man was referred for evaluation after trauma to the left eye. He gave a history of familial adenomatous polyposis (FAP) diagnosed at age 15 years and treated with prophylactic colectomy. Funduscopy revealed multifocal pigmented ocular fundus lesions at the level of the retinal pigment epithelium (RPE) in both eyes (Figure 1A and 1B). The lesions were haphazardly distributed, oval-shaped, variable in size, and with irregular borders. On fundus autofluorescence, the RPE lesions were hypoautofluorescent and surrounded by trace hyperautofluorescence (Figure 1C and 1D). These findings represented the pigmented ocular fundus lesions that serve as a biomarker for FAP. [Ophthalmic Surg Lasers Imaging Retina. 2020;51:124.].
一名36岁男性因左眼外伤前来接受评估。他有家族性腺瘤性息肉病（FAP）病史，15岁时被诊断出该病，并接受了预防性结肠切除术。眼底检查发现双眼视网膜色素上皮（RPE）水平有多发性色素性眼底病变（图1A和1B）。病变分布不规则，呈椭圆形，大小不一，边界不规则。在眼底自发荧光检查中，RPE病变呈低自发荧光，周围有微量高自发荧光（图1C和1D）。这些发现代表了作为FAP生物标志物的色素性眼底病变。[《眼科手术、激光与视网膜成像》。2020；51：124。]
