糖尿病视网膜病变患者白内障术后黄斑水肿与视力观察。

Macular Edema and Visual Acuity Observation after Cataract Surgery in Patients with Diabetic Retinopathy.

机构信息

Department of Ophthalmology, Yantai Yuhuangding Hospital, Yantai 264000, Shandong Province, China.

出版信息

J Healthc Eng. 2022 Jan 25;2022:3311751. doi: 10.1155/2022/3311751. eCollection 2022.

DOI:10.1155/2022/3311751

PMID:35126918

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8808216/

Abstract

OBJECTIVE

The purpose was to explore the effect of cataract surgery on postoperative macular edema and visual acuity in patients with diabetic retinopathy.

METHODS

88 patients with diabetic retinopathy treated in our hospital (December 2019-December 2020) were chosen as research subjects and divided into experimental group of 44 patients (52 eyes) and control group of 44 patients (54 eyes) according to the odd and even admission numbers. The control group received laser photocoagulation treatment, while the experimental group underwent cataract surgery. The central macular thickness (CMT) and visual acuity of the two groups after treatment were detected to evaluate the therapeutic effect of different treatment methods on diabetic retinopathy.

RESULTS

No obvious differences in sex ratio, average age, average course of disease, average weight, average BMI, average glycosylated hemoglobin, and residence were found between the two groups ( > 0.05). The total clinical effective rate in the experimental group was obviously higher compared with the control group ( < 0.05). The CMT at T1, T2, and T3 in the experimental group was obviously lower compared with the control group ( < 0.05). The BCVA in the experimental group at 1 month and 3 months after treatment was obviously higher compared with the control group ( < 0.05). The VEGF levels of both groups after treatment were obviously lower ( < 0.001), and the VEGF level in the experimental group after treatment was obviously lower compared with the control group ( < 0.001). The total incidence of complications in the experimental group was obviously lower compared with the control group ( < 0.05).

CONCLUSION

Cataract surgery is a reliable method to improve visual acuity and reduce serum inflammatory indicators in patients with diabetic retinopathy, with better clinical effect than laser photocoagulation, which is recommended for the treatment of diabetic retinopathy.

摘要

目的

探讨白内障手术对糖尿病视网膜病变患者术后黄斑水肿及视力的影响。

方法

选取我院收治的 88 例糖尿病视网膜病变患者（2019 年 12 月-2020 年 12 月）作为研究对象，根据入院单双号分为实验组 44 例（52 眼）和对照组 44 例（54 眼）。对照组行激光光凝治疗，实验组行白内障手术。检测两组治疗后的中心黄斑厚度（CMT）和视力，评估不同治疗方法对糖尿病视网膜病变的疗效。

结果

两组性别比、平均年龄、平均病程、平均体质量、平均 BMI、平均糖化血红蛋白、居住情况比较，差异无统计学意义（>0.05）。实验组总有效率明显高于对照组（<0.05）。实验组 T1、T2、T3 时 CMT 明显低于对照组（<0.05）。实验组治疗后 1 个月、3 个月时 BCVA 明显高于对照组（<0.05）。两组治疗后 VEGF 水平均明显降低（<0.001），实验组治疗后 VEGF 水平明显低于对照组（<0.001）。实验组总并发症发生率明显低于对照组（<0.05）。