Gunasekaran T, Olivier N B, Sanders R A
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Veterinary Medical Center, 736 Wilson Rd, East Lansing, MI, 48824, USA.
Department of Small Animal Clinical Sciences, College of Veterinary Medicine, Veterinary Medical Center, 736 Wilson Rd, East Lansing, MI, 48824, USA.
J Vet Cardiol. 2020 Feb;27:78-87. doi: 10.1016/j.jvc.2020.01.003. Epub 2020 Feb 4.
The primary objective of this study was to test whether seven-day Holter recording improves the sensitivity of detecting dilated cardiomyopathy (DCM) predictive criteria (DCM) compared with 24-h Holter recording in asymptomatic Doberman Pinscher (DP) dogs.
Twenty-eight asymptomatic DP dogs with normal echocardiographic examinations.
Dogs with normal echocardiographic examinations underwent seven-day Holter monitoring. The presence of ≥50 ventricular premature complexes and or ≥ one couplet/one triplet/one episode of ventricular tachycardia per 24-h period was considered positive for DCM.
Five dogs were positive on the first day, and an additional six dogs tested positive from day two to seven of the Holter recording. The number of dogs positive for DCM detected by four days was significantly different (p = 0.031) compared with the first-day Holter recording.
Seven-day Holter recording detected significantly more dogs with DCM compared with the first-day Holter recording. Follow-up studies are warranted to evaluate the long-term accuracy of multiple-day Holter analysis in predicting the development of DCM in DP dogs.
本研究的主要目的是测试与24小时动态心电图记录相比，七天动态心电图记录是否能提高检测无症状杜宾犬扩张型心肌病（DCM）预测标准的敏感性。
28只超声心动图检查正常的无症状杜宾犬。
超声心动图检查正常的犬接受七天动态心电图监测。每24小时出现≥50次室性早搏和/或≥1次成对/三联律/室性心动过速发作被视为DCM阳性。
5只犬在第一天呈阳性，另外6只犬在动态心电图记录的第二天至第七天检测呈阳性。与第一天的动态心电图记录相比，四天时检测出的DCM阳性犬数量有显著差异（p = 0.031）。
与第一天的动态心电图记录相比，七天动态心电图记录检测出的DCM阳性犬明显更多。有必要进行后续研究，以评估多天动态心电图分析预测杜宾犬DCM发展的长期准确性。
