Ye M, Tu G Y
Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Zhong Liu Za Zhi. 1988 Mar;10(2):129-31.
The TNM staging of maxillary sinus cancer was stipulated by the UICC in 1987 using Ohngren line of demarcation. This report is to discuss the applicability of this staging based on 232 cases of maxillary sinus cancer treated in this hospital. Of 232 cases, the 3-year survival rate for those who received surgery alone was 4/6, for those after radical irradiation, 15.6% (20/128) and for those by combined irradiation and surgery, 43.9% (43/98). The 3-year survival rate for the whole series was 28.9%. To analyze the survival rates of different types of lesion separately, we found that those with involvement of the posterior wall, hence invading the pterygopalatine fossa had poor prognosis with a three year survival rate of 19.5%. And invasion of soft and/or hard palate also gave poor survival. Contrary to the common consensus, invasion of ethmoidal sinuses did not pose a serious prognosis. The feasibility of the Ohngren line in TNM staging was thus questioned. On the basis of our data, a modification of the TNM staging of JJC for maxillary sinus cancer is suggested.
上颌窦癌的TNM分期由国际抗癌联盟（UICC）于1987年采用昂格伦（Ohngren）分界线予以规定。本报告旨在根据本院治疗的232例上颌窦癌病例探讨该分期的适用性。在这232例病例中，单纯接受手术者的3年生存率为4/6，接受根治性放疗者为15.6%（20/128），接受放疗与手术联合治疗者为43.9%（43/98）。整个系列的3年生存率为28.9%。为分别分析不同类型病变的生存率，我们发现累及后壁从而侵犯翼腭窝者预后较差，3年生存率为19.5%。侵犯软腭和/或硬腭者生存率也较低。与普遍观点相反，筛窦受侵并未造成严重的预后。因此，昂格伦线在TNM分期中的可行性受到质疑。根据我们的数据，建议对上颌窦癌的国际抗癌联盟TNM分期进行修订。
