Department of Orthopedic Surgery, Spine Center, Changzheng Hospital, Second Military Medical University, No. 415 Fengyang Road, Shanghai, 200003, People's Republic of China.
Department of Emergency and Critical Care, Changzheng Hospital, Second Military Medical University, No. 415 Fengyang Road, Shanghai, 200003, People's Republic of China.
Int Orthop. 2020 May;44(5):935-945. doi: 10.1007/s00264-020-04508-x. Epub 2020 Feb 21.
This is a prospective case-controlled study.
The purpose of this study is to investigate the effect of a modified transforaminal lumbar interbody fusion (TLIF) on the immediate post-operative symptoms in patients with lumbar disc herniation (LDH) accompanied with stenosis.
A total of 204 LDH patients with single-level TLIF were enrolled. According to the sequence of the placement of rods and cage, patients were divided into group R (rod-prior-to-cage) and group C (cage-prior-to-rod). Neurological function was evaluated by the Japanese Orthopedic Association (JOA) score. Radiological assessment includes height of intervertebral space (HIS), foraminal height (FH), foraminal area (FA), and segmental lordosis (SL). Change of original symptoms (pain/numb) and new-onset symptoms (pain/numb) after surgery were also recorded.
Patients in group R had less change of HIS at L3/4, L4/5, and L5/S1 levels compared with pre-operation (all p > 0.05), whereas group C had larger change (all p < 0.05). No statistical difference was found in FH between the two groups before and after surgery at L3/4, L4/5, and L5/S1, respectively (all p > 0.05). In terms of FA, patients in group R had better improvement after surgery than those in group C at L3/4 and L4/5 (both p < 0.05). Patients in both groups acquired good improvement of neurological function. However, there were fewer patients in group R who experienced post-operative leg pain or numb compared with those in group C (p < 0.05).
The modified open TLIF can significantly reduce the incidence of immediate post-operative symptoms for patients with single-level lumbar disc herniation via installation of rods prior to insertion of cage and the "neural standard" should serve as the goal of decompression for spine surgeons to restore disc/foraminal height and to minimize nerve distraction.
这是一项前瞻性病例对照研究。
本研究旨在探讨改良经椎间孔腰椎体间融合术(TLIF)对伴有狭窄的腰椎间盘突出症(LDH)患者术后即刻症状的影响。
共纳入 204 例接受单节段 TLIF 的 LDH 患者。根据棒和笼的放置顺序,患者分为 R 组(棒先于笼)和 C 组(笼先于棒)。采用日本骨科协会(JOA)评分评估神经功能。影像学评估包括椎间高度(HIS)、椎间孔高度(FH)、椎间孔面积(FA)和节段前凸角(SL)。记录术后原有症状(疼痛/麻木)和新发症状(疼痛/麻木)的变化。
R 组患者在 L3/4、L4/5 和 L5/S1 水平的 HIS 术后变化较术前无统计学差异(均 p>0.05),而 C 组变化较大(均 p<0.05)。两组患者在 L3/4、L4/5 和 L5/S1 水平的 FH 在术前和术后均无统计学差异(均 p>0.05)。在 FA 方面,R 组患者术后改善优于 C 组(均 p<0.05)。两组患者术后神经功能均得到良好改善。然而,与 C 组相比,R 组术后发生腿部疼痛或麻木的患者较少(p<0.05)。
改良后路 TLIF 先放置棒后插入笼可显著降低单节段腰椎间盘突出症患者术后即刻症状的发生率,脊柱外科医生应以“神经标准”作为减压的目标,以恢复椎间盘/椎间孔高度,尽量减少神经牵张。