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老年女性乳腺癌的外科治疗——244例患者分析

[Surgical treatment of breast cancer in elderly women--analysis of 244 patients].

作者信息

Zhan Y Q, Li G C

机构信息

Tumor Hospital, Zhongshan University of Medical Sciences, Guangzhou.

出版信息

Zhonghua Zhong Liu Za Zhi. 1988 Mar;10(2):149-51.

PMID:3208657
Abstract

From April 1964 to December 1981, 244 patients, women over 60 years old, with unilateral breast cancer were treated by surgery in our hospital. In this series, 15 patients (6.1%) had Stage I, 131 (53.6%) Stage II, 82 (33.6%) Stage III and 16 (6.6%) unstaged lesions. Of these patients, 3 were treated by extended radical mastectomy (ERM), 140 by standard radical mastectomy (SRM), 49 by modified radical mastectomy (MRM) and 52 by total mastectomy (TM). Except 52 cases by TM, axillary lymph node metastasis rate in 192 patients of this series was 49.3%. The 5- and 10-year survival rates were 33.3% in ERM group, 53.4% and 39.5% in SRM group, 70.8% and 48.5% in MRM group, and 73.4% and 55.3% in TM group, respectively. The overall 5-and 10-year survival rates were 62.1% and 45.6%. In Stage I, II patients, the 5-and 10-year survival rates of TM group were much higher than those of SRM and MRM groups (P less than 0.01), but in Stage III, the 5- and 10-year survival rates of MRM group were higher than those of other groups (P less than 0.05). Noticeably, the 5- and 10-year survival rates of SRM group in Stage I approximately III were not satisfactory. Our data show that the postoperative radiotherapy or chemotherapy was ineffective in elderly patients with breast cancer.

摘要

1964年4月至1981年12月,我院对244例60岁以上的单侧乳腺癌女性患者进行了手术治疗。在这组病例中,15例(6.1%)为Ⅰ期,131例(53.6%)为Ⅱ期,82例(33.6%)为Ⅲ期,16例(6.6%)为分期不明的病变。这些患者中,3例行扩大根治性乳房切除术(ERM),140例行标准根治性乳房切除术(SRM),49例行改良根治性乳房切除术(MRM),52例行全乳房切除术(TM)。除52例行TM的病例外,该组192例患者的腋窝淋巴结转移率为49.3%。ERM组的5年和10年生存率分别为33.3%,SRM组为53.4%和39.5%,MRM组为70.8%和48.5%,TM组为73.4%和55.3%。总的5年和10年生存率分别为62.1%和45.6%。在Ⅰ、Ⅱ期患者中,TM组的5年和10年生存率远高于SRM组和MRM组(P<0.01),但在Ⅲ期患者中,MRM组的5年和10年生存率高于其他组(P<0.05)。值得注意的是,Ⅰ期至Ⅲ期患者中SRM组的5年和10年生存率并不理想。我们的数据表明,术后放疗或化疗对老年乳腺癌患者无效。

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