Zhang Q Y, Ma L M, Tang Z Q
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2020 Jan;34(1):83-85. doi: 10.13201/j.issn.1001-1781.2020.01.020.
The trichilemmal carcinoma is a rare tumor that usually occurs on sun-exposed skin, especially on the face, scalp, neck and back of hands, mainly in elderly subjects but commonly between the 4th and 9th decades of life. We report a case of giant trichilemmal carcinoma. A 65-year-old man presented with a 5-year history of a slowly developing mass arising from his right retroauricular region, with local destruction of the auricle. The lesion appeared as a 8.0 cm×6.5 cm×2.0 cm sized, with surface ulceration and erosion, subcutaneous nodule, and mild tenderness. Preoperative pathological biopsy showed: "retroauricular" trichilemmal carcinoma. The patient underwent right retroauricular tumor resection, partial auriculectomy, neck adjacent skin flap repair and auricle reconstruction. Postoperative pathological report: "retroauricular" trichilemmal carcinoma. The margin of incision was negative, and the lymph nodes in zone II were negative. Immunohistochemistry: Tumor cells were CK5/6（++）, p63（++）, p40（++）, CD10（-）, EMA（-）, Ki-67（+, about 60%）.
外毛根鞘癌是一种罕见肿瘤，通常发生于暴露于阳光下的皮肤，尤其是面部、头皮、颈部和手背，主要见于老年人，但常见于40至90岁之间。我们报告一例巨大外毛根鞘癌病例。一名65岁男性，右耳后区域出现缓慢生长肿物5年，伴有耳廓局部破坏。病变大小为8.0 cm×6.5 cm×2.0 cm，表面有溃疡和糜烂，皮下有结节，并有轻度压痛。术前病理活检显示：“耳后”外毛根鞘癌。患者接受了右耳后肿瘤切除、部分耳廓切除术、颈部邻位皮瓣修复及耳廓重建术。术后病理报告：“耳后”外毛根鞘癌。切口边缘阴性，II区淋巴结阴性。免疫组化：肿瘤细胞CK5/6（++）、p63（++）、p40（++）、CD10（-）、EMA（-）、Ki-67（+，约60%）。
