Agriculture and Agri-Food Canada, Sherbrooke Research and Development Centre, Sherbrooke, QC J1M 0C8, Canada.
J Anim Sci. 2020 Mar 1;98(3). doi: 10.1093/jas/skaa063.
The present study compares the net portal appearance of dietary iron (Fe) and selenium (Se) after meals containing different sources and levels of these minerals. Twelve pigs (55.1 ± 3.7 kg) were used in a cross-over design to assess the 11-h net portal-drained viscera (PDV) flux of serum Fe and Se after ingestion of boluses containing inorganic (I) or organic (O) dietary Fe and Se at industry average (A; 200 and 0.6 mg, respectively) or high (H; 400 and 1.2 mg, respectively) levels. Arterial serum Fe concentrations increased by an average of 158% within 6 h post-meal and gradually decreased thereafter (P < 0.001). Values were greater (P < 0.001) for I than for O until 6 h post-meal and greater (P ≤ 0.001) for A than for H from 4 to 8 h post-meal. For the whole post-prandial period (11 h), arterial serum Fe concentrations tended (P = 0.06) to be greater for I than for O and were lowest for HO (P ≤ 0.03). Net PDV flux of Fe tended to be greater for AI than for AO (P ≥ 0.07). Cumulative appearance of Fe in PDV serum (% of dietary intake) was greater for I than for O (2.43 vs. -0.76%; P = 0.02) and A tended to be greater than H (1.96 vs. -0.29 %; P = 0.09) until 3 h post-meal, but these effects further faded out (P ≥ 0.43). Arterial serum Se concentration decreased for all treatments (average of 7%) from premeal values (P < 0.001), and this was more pronounced for O than for I (P = 0.03). Irrespective of treatment, net PDV flux of Se was positive (different from 0, P ≤ 0.03) during the first 90 min post-meal, decreased to negative minimum values (different from 0, P = 0.03) at 5 h post-meal, and was not different from 0 thereafter (P ≥ 0.11). Cumulative appearance of Se in PDV serum (% of dietary intake) was greater for I than for O (20.0 vs. -3.8%; P = 0.04) only at 45 min post-meal. In conclusion, both dietary Fe and Se absorption are limited to the early post-meal period. Whereas for Fe, the level effect is in accordance with the known negative correlation between its dietary concentration and percentage of intestinal absorption, this was not the case for dietary Se. The postabsorptive availability of dietary I was greater than O for both minerals and, particularly for Fe, at low levels.
本研究比较了膳食铁（Fe）和硒（Se）在餐后不同来源和水平下的净门静脉外观。12 头猪（55.1 ± 3.7 公斤）采用交叉设计，评估摄入含有不同水平无机（I）或有机（O）铁和硒（分别为 200 和 0.6 毫克）或高（H；分别为 400 和 1.2 毫克）的 bolus 后 11 小时门静脉引流内脏（PDV）的血清 Fe 和 Se 的净流量。动脉血清 Fe 浓度在餐后 6 小时内平均增加 158%，此后逐渐下降（P < 0.001）。与 O 相比，I 在餐后 6 小时内更高（P < 0.001），与 H 相比，4 至 8 小时内更高（P ≤ 0.001）。对于整个餐后期（11 小时），I 比 O 更倾向于（P = 0.06），HO 最低（P ≤ 0.03）。Fe 的净 PDV 流量倾向于 AI 比 AO 更高（P ≥ 0.07）。PDV 血清中 Fe 的累积出现量（膳食摄入量的百分比）I 比 O 更高（2.43 对 -0.76%；P = 0.02），A 比 H 更高（1.96 对 -0.29%；P = 0.09），直到 3 小时餐后，但这些影响进一步消失（P ≥ 0.43）。所有处理的动脉血清 Se 浓度均从餐前值下降（平均 7%）（P < 0.001），O 比 I 更明显（P = 0.03）。无论治疗如何，Se 的净 PDV 流量在餐后 90 分钟内呈阳性（与 0 不同，P ≤ 0.03），在 5 小时餐后达到负最小值（与 0 不同，P = 0.03），此后与 0 无差异（P ≥ 0.11）。PDV 血清中 Se 的累积出现量（膳食摄入量的百分比）I 比 O 更高（20.0 对 -3.8%；P = 0.04），仅在餐后 45 分钟。总之，膳食 Fe 和 Se 的吸收都局限于餐后早期。虽然对于 Fe 来说，水平效应与已知的其膳食浓度和肠道吸收率之间的负相关一致，但对于膳食 Se 来说并非如此。两种矿物质的肠道吸收后 I 的可用性均大于 O，尤其是在低水平时的 Fe。
