Pykhtina A A, Gladkova N E
Farmakol Toksikol. 1988 Sep-Oct;51(5):72-4.
The study of the effect of a new antitumor drug cortifen on humoral immunity in experiments on CBA mice showed that it is a potent and long acting immunodepressant. The degree of immunity depression was found to be drug dose-dependent. The hormonal components of cortifen failed to exert the immunodepressive action. The alkylating component, chlorphenacyl, on the contrary, had the immunostimulating effect.
