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前列腺素对培养的大鼠睾丸间质细胞激素功能的影响。

Effect of prostaglandins on hormonal function of cultured rat Leydig cells.

作者信息

Bilińska B, Wojtusiak A

机构信息

Department of Animal Physiology, Jagellonian University, Kraków, Poland.

出版信息

Folia Histochem Cytobiol. 1988;26(2):53-9.

PMID:3208911
Abstract

The effect of PGF2 alpha and its analogues on androgen production and activity of delta 5,3 beta-hydroxysteroid dehydrogenase in rat Leydig cells in vitro was investigated. Prostaglandin of the F type inhibit the enzyme activity and hormone secretion by cultured Leydig cells. This effect was considerably stronger in Leydig cells isolated from mature rats, than by Leydig cells from immature animals.

摘要

研究了前列腺素F2α及其类似物对体外培养的大鼠睾丸间质细胞雄激素生成及δ5,3β-羟基类固醇脱氢酶活性的影响。F型前列腺素可抑制培养的睾丸间质细胞的酶活性和激素分泌。这种作用在从成熟大鼠分离的睾丸间质细胞中比从未成熟动物的睾丸间质细胞中更强。

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