高渗介质引起的艾氏腹水瘤细胞形态变化
Changes in the morphology of Ehrlich ascites tumour cells caused by hyperosmotic media.
作者信息
Kajstura J, Korohoda W
机构信息
Department of Cell Biology, Jan Zurzycki Institute of Molecular Biology, Jagellonian University, Kraków, Poland.
出版信息
Folia Histochem Cytobiol. 1988;26(2):91-7.
It was found that Ehrlich ascites tumour cells undergo significant morphology changes in media in which osmolarity is increased by NaCl or Hanks' balanced salt solution. The morphology changes include formation of filopodia- and lamellipodia-like cell surface protrusions. Their formation is enhanced by an addition of cytochalasin B. The data obtained suggest that both changes in plasma membrane properties and changes in activity of contractile apparatus participate in the formation of cell surface protrusions.
研究发现，艾氏腹水瘤细胞在通过氯化钠或汉克斯平衡盐溶液提高渗透压的培养基中会发生显著的形态变化。形态变化包括形成丝状伪足和片状伪足样的细胞表面突起。细胞松弛素B的添加会增强它们的形成。所获得的数据表明，质膜性质的变化和收缩装置活性的变化都参与了细胞表面突起的形成。
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