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A型主动脉夹层开放修复术后主动脉弓血管内治疗的技术适应证

Technical eligibility for endovascular treatment of the aortic arch after open type A aortic dissection repair.

作者信息

Budtz-Lilly Jacob, Vikholm Per, Wanhainen Anders, Astudillo Rafael, Thelin Stefan, Mani Kevin

机构信息

Section of Vascular Surgery, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden; Department of Vascular Surgery, Aarhus University Hospital, Aarhus, Denmark.

Section of Thoracic Surgery, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.

出版信息

J Thorac Cardiovasc Surg. 2021 Sep;162(3):770-777. doi: 10.1016/j.jtcvs.2019.12.113. Epub 2020 Jan 28.

Abstract

OBJECTIVE

The objective was to report on the technical eligibility of patients previously treated for Stanford type A aorta dissection for endovascular aortic arch repair based on contemporary anatomic criteria for an arch inner-branched stent graft.

METHODS

All patients treated for type A aorta dissection from 2004 to 2015 at a single aortic center were identified. Extent of repair and use of circulatory arrest were reported. Survival and reoperation were assessed using Kaplan-Meier and competing risk models. Anatomic assessment was performed using 3-dimensional computed tomography imaging software. Primary outcome was survival of 1 year or more and fulfillment of the arch inner-branched stent graft anatomic criteria.

RESULTS

A total of 198 patients were included (158 DeBakey I, 32 DeBakey II, and 8 intramural hematoma). Mortality was 30 days (16.2%), 1 year (16.3%), and 10 years (45.0%). A total of 129 patients had imaging beyond 1 year (mean, 47.8 months), and 89 patients (69.0%) were eligible for arch inner-branched stent grafting. During follow-up, 19 patients (14.7%) met the threshold criteria for aortic arch treatment, of whom 14 (73.7%) would be considered eligible for arch inner-branched stent graft. Patients who underwent type A aorta dissection repair with circulatory arrest and no distal clamp were more often eligible for endovascular repair (88.8%) than those operated with a distal clamp (72.5%; P = .021). Among patients who did not meet the arch inner-branched stent graft anatomic criteria, the primary reasons were mechanical valve (40%) and insufficient proximal seal (30%).

CONCLUSIONS

More than two-thirds of patients post-type A aorta dissection repair are technically eligible for endovascular arch inner-branched stent graft repair. The development of devices that can accommodate a mechanical aortic valve and a greater awareness of sufficient graft length would significantly increase availability.

摘要

目的

根据当代弓部内分支支架型人工血管的解剖学标准,报告既往接受过Stanford A型主动脉夹层治疗的患者行血管腔内主动脉弓修复术的技术适宜性。

方法

确定2004年至2015年在单一主动脉中心接受A型主动脉夹层治疗的所有患者。报告修复范围及循环阻断的使用情况。采用Kaplan-Meier法和竞争风险模型评估生存情况及再次手术情况。使用三维计算机断层扫描成像软件进行解剖学评估。主要结局为存活1年及以上且符合弓部内分支支架型人工血管解剖学标准。

结果

共纳入198例患者(158例DeBakey I型、32例DeBakey II型和8例壁内血肿)。30天死亡率为16.(2%),1年死亡率为16.3%,10年死亡率为45.0%。共有129例患者有超过1年的影像学资料(平均47.8个月),89例患者(69.0%)适合行弓部内分支支架型人工血管植入术。在随访期间,19例患者(14.7%)达到主动脉弓治疗的阈值标准,其中14例(73.7%)被认为适合行弓部内分支支架型人工血管植入术。与使用远端阻断钳进行手术的患者(72.5%;P = 0.021)相比,接受循环阻断且未使用远端阻断钳的A型主动脉夹层修复患者更常适合行血管腔内修复(88.8%)。在不符合弓部内分支支架型人工血管解剖学标准的患者中,主要原因是机械瓣膜(40%)和近端密封不足(30%)。

结论

超过三分之二的A型主动脉夹层修复术后患者在技术上适合行血管腔内弓部内分支支架型人工血管修复术。能够容纳机械主动脉瓣膜的器械的研发以及对足够移植物长度的更高认识将显著提高其可用性。

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