Padmanabhan Harini, Kumar Anand V, Shivashankar K
Department of Prosthodontics, Sri Ramachandra Institute of Higher Education and Research, Chennai, Tamil Nadu, India.
Department of Public Health Dentistry, Indira Gandhi Institute of Dental Sciences, Kothamangalam, Kerala, India.
J Indian Prosthodont Soc. 2020 Jan-Mar;20(1):17-26. doi: 10.4103/jips.jips_373_19. Epub 2020 Jan 27.
Implantology has been widely accepted as the mainstay treatment for rehabilitating complete and partial edentulism. However, it is associated with some failures and complications, the most concerning being neurosensory disturbance. Although neurosensory disturbance has been extensively studied, the incidence and cause remains largely variable. Thus, the aim of this systematic review and meta-analysis was to evaluate the incidence, distribution, and recovery rate of neurosensory disturbance.
This systematic review was conducted as per the Preferred Reporting Items for Systematic Reviews and Meta-analyses statement. A structured literature review was conducted using the following databases: PubMed, Science Direct, Cochrane, Ovid, and Google Scholar for reports related to neurosensory disturbance experienced after implant placement in the mandible.
Incidence and recovery rate for 100 person-years was calculated using the Poisson regression model. The risk difference of incidence between anterior and posterior implants was calculated with a random effects model.
Electronic database search yielded 1589 articles; a total of nine articles were selected for the meta-analysis. The risk of neurosensory disturbance was estimated at 13.50/100 person-years (95% confidence interval (CI): 10.98-16.03), with a greater risk with anteriorly placed implants: -0.02 (95% CI: -0.21-0.16) ( = 0.05). The overall recovery rate was estimated at 51.30/100 person-years (95% CI: 31.2-71.4).
Within the limitations of the study, it can be concluded that mandibular implant placement is associated with a considerable risk of neurosensory disturbance. A large proportion of these patients present with spontaneous recovery; however, clinicians must take necessary precautions to avoid such complications. More randomized controlled trials are required to quantify the effect of factors leading to altered sensation during implant placement.
种植学已被广泛认可为修复全口和部分牙列缺失的主要治疗方法。然而,它会伴有一些失败病例和并发症,其中最令人担忧的是神经感觉障碍。尽管对神经感觉障碍已进行了广泛研究,但其发生率和病因仍有很大差异。因此,本系统评价和荟萃分析的目的是评估神经感觉障碍的发生率、分布情况及恢复率。
本系统评价按照系统评价和荟萃分析的首选报告项目声明进行。使用以下数据库进行结构化文献检索:PubMed、科学Direct、Cochrane、Ovid和谷歌学术,以查找与下颌种植术后发生的神经感觉障碍相关的报告。
采用泊松回归模型计算每100人年的发生率和恢复率。使用随机效应模型计算前后位种植体发生率的风险差异。
电子数据库检索得到1589篇文章;共筛选出9篇文章进行荟萃分析。神经感觉障碍的风险估计为每100人年13.50例(95%置信区间(CI):10.98 - 16.03),前部种植体的风险更高:-0.02(95%CI:-0.21 - 0.16)(P = 0.05)。总体恢复率估计为每100人年51.30例(95%CI:31.2 - 71.4)。
在本研究的局限性范围内,可以得出结论,下颌种植与相当大的神经感觉障碍风险相关。这些患者中有很大一部分会出现自发恢复;然而,临床医生必须采取必要的预防措施以避免此类并发症。需要更多的随机对照试验来量化种植过程中导致感觉改变的因素的影响。