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采用带同种异体骨的钢板-螺钉-棒系统进行枕颈融合治疗颅颈交界区不稳的手术、临床及影像学结果

Surgical, clinical, and radiological outcomes of occipitocervical fusion using the plate-screw-rod system with allograft in craniocervical instability.

作者信息

Upadhyaya Mihir, Jain Sanyam, Kire Neilakuo, Merchant Zahir, Kundnani Vishal, Patel Ankit

机构信息

Bombay Hospital and Research Centre, Mumbai, Maharashtra, India.

出版信息

J Craniovertebr Junction Spine. 2019 Oct-Dec;10(4):216-223. doi: 10.4103/jcvjs.JCVJS_87_19. Epub 2020 Jan 23.

Abstract

OBJECTIVE

We evaluated surgical, clinical, and radiological outcomes of posterior occipitocervical fusion (OCF) using plate-rod-screw construct supplemented with allograft in cases of occipitocervical instability.

STUDY DESIGN

This was a retrospective analysis of prospective collected data.

METHODS

Data of 52 patients who underwent posterior OCF using plate-screw-rod construct supplemented with allograft at a single institute from 2009 to 2014 were analyzed. Demographics, clinical parameters (Visual Analog Score [VAS], ODI, and mJOA score), functional status (McCormick scale), radiological parameters - mean atlantodens interval, posterior occipitocervical angle, occipitocervical 2 angle, and surgical parameters (operative time, blood loss, hospital stay, and fusion) with complications were evaluated.

RESULTS

The mean age of the patients was 54.56 ± 16.21 years with male: female was 28:24. The mean operative time was 142.2 min (90-185 min) and mean blood loss was 250.8 ml. The mean duration of hospital stay was 6.7 days and mean follow-up period was 65.17 ± 5.39 months. There was significant improvement in clinical parameters (modified JOA score, VAS, and Oswestry Disability Index values) postoperatively. Forty patients showed recovery in neurological status at least in Grade 1 in McCormick scale with no neurological deterioration in any patient. Furthermore, radiological parameters at cervicomedullary junction got into acceptable range. Implant-related complications noted in 1 patient and 1 patient had vertebral artery injury. We had dural tear in 3 patients and infection in 2 patients. Fusion was achieved in 46 cases with mean time for fusion was 11.039 months.

CONCLUSION

Patients with occipitocervical instability can successfully undergo posterior OCF using plate-screw-rod construct supplemented with allograft with high fusion rate, good clinical and functional outcomes, and low complication rate.

摘要

目的

我们评估了在枕颈不稳病例中,使用钢板 - 棒 - 螺钉结构并辅以同种异体骨进行后路枕颈融合术(OCF)的手术、临床和影像学结果。

研究设计

这是一项对前瞻性收集数据的回顾性分析。

方法

分析了2009年至2014年在单一机构接受使用钢板 - 螺钉 - 棒结构并辅以同种异体骨的后路OCF的52例患者的数据。评估了人口统计学、临床参数(视觉模拟评分[VAS]、ODI和改良日本骨科学会[mJOA]评分)、功能状态(麦考密克量表)、影像学参数 - 平均寰齿间距、枕颈后角、枕颈2角,以及手术参数(手术时间、失血量、住院时间和融合情况)及并发症。

结果

患者的平均年龄为54.56±16.21岁,男性与女性比例为28:24。平均手术时间为142.2分钟(90 - 185分钟),平均失血量为250.8毫升。平均住院时间为6.7天,平均随访期为65.17±5.39个月。术后临床参数(改良JOA评分、VAS和奥斯维斯特里残疾指数值)有显著改善。40例患者在麦考密克量表中神经功能至少恢复到1级,且无患者神经功能恶化。此外,颈髓交界处的影像学参数进入可接受范围。1例患者出现植入物相关并发症,1例患者发生椎动脉损伤。3例患者出现硬脑膜撕裂,2例患者发生感染。46例实现融合,平均融合时间为11.039个月。

结论

枕颈不稳患者使用钢板 - 螺钉 - 棒结构并辅以同种异体骨成功进行后路OCF,融合率高,临床和功能结果良好,并发症发生率低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/63b2/7008657/7ff5eea94a81/JCVJS-10-216-g001.jpg

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