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牙髓石作为冠状动脉疾病的风险预测指标

Pulp Stones as Risk Predictors for Coronary Artery Disease.

作者信息

Babu Suresh J, Swarnalatha C, Rao Amit P, Kumar Barun B, Tilak Balagangadhar P, Naidu Ramesh B, Nayyar Abhishek Singh

机构信息

Department of Preventive Dental Sciences, Division of Periodontology, College of Dentistry, University of Ha'il, Ha'il, Kingdom of Saudi Arabia.

Department of Oral and Maxillofacial Surgery, Dr.Hedgewar Smruti Rugna Seva Mandal's Dental College and Hospital, Hingoli, Maharashtra, India.

出版信息

Int J Prev Med. 2020 Jan 24;11:7. doi: 10.4103/ijpvm.IJPVM_68_19. eCollection 2020.

Abstract

BACKGROUND

Coronary artery disease (CAD) has been the leading cause of morbidity and mortality worldwide. Studies indicate that patients with CAD show higher degree of pulp calcifications. Localized pulp calcifications are microscopically apparent in more than half of the teeth in young adolescents. However, pulp stones extending to the entire dentition are infrequent and need further evaluation to predict the risk of other probabilities of associated diseases. The present study was planned to estimate the prevalence of pulp stones in patients diagnosed with or, undergoing treatment for CAD.

METHODS

The present study consisted of 300 subjects within an age range of 20-55 years who were divided into the study group consisting of 150 patients including 108 males and 42 females as well as 150 age- and sex-matched healthy controls. Pulp stones were imaged using bitewing radiographs using paralleling technique under standard conditions.

STATISTICAL ANALYSIS USED

The statistical analysis was performed using IBM SPSS statistics 20 Core system software (SPSS Inc., Chicago, IL, USA) while Chi-square test was used to check the prevalence of pulp stones in patients with CAD in addition to their arch-wise and region-wise distribution. value <0.05 was considered statistically significant.

RESULTS

The present study revealed 100% prevalence of pulp stones in the study group while 90% of the subjects in the control group were also afflicted with pulp stones, though the total number of pulp calcifications observed were lesser in number in the control group compared to the study group ( < 0.05). No significant difference was found, although in the gender predilection for the development of pulp stones in the study group while the control group revealed a definite male predilection with around 96.24% of the males afflicted with pulp stones ( < 0.05). Furthermore, maxillary teeth had a statistically significant predilection for the development of pulp stones in both the study as well as the control groups ( < 0.05).

CONCLUSIONS

The patients with CAD have high chance of being affected with pulp stones. Higher prevalence of this entity in multiple teeth may warrant such an individual, in the presence of other compounding risk factors, as a candidate for CAD to be ruled out.

摘要

背景

冠状动脉疾病(CAD)一直是全球发病和死亡的主要原因。研究表明,CAD患者牙髓钙化程度更高。在青少年中,超过半数牙齿在显微镜下可见局部牙髓钙化。然而,累及全口牙列的髓石并不常见,需要进一步评估以预测其他相关疾病的风险。本研究旨在评估被诊断为CAD或正在接受CAD治疗的患者中髓石的患病率。

方法

本研究纳入300名年龄在20 - 55岁之间的受试者,分为研究组和对照组,每组150人。研究组包括150例患者,其中男性108例,女性42例;对照组为150名年龄和性别匹配的健康受试者。在标准条件下,使用平行投照技术拍摄咬合翼片对髓石进行成像。

统计分析方法

使用IBM SPSS statistics 20核心系统软件(美国伊利诺伊州芝加哥市SPSS公司)进行统计分析,采用卡方检验来检查CAD患者中髓石的患病率及其按牙弓和区域的分布情况。P值<0.05被认为具有统计学意义。

结果

本研究显示研究组髓石患病率为100%,而对照组90%的受试者也患有髓石,尽管对照组观察到的牙髓钙化总数比研究组少(P<0.05)。研究组在髓石形成的性别偏好方面未发现显著差异,而对照组显示出明显的男性偏好,约96.24%的男性患有髓石(P<0.05)。此外,在研究组和对照组中,上颌牙在髓石形成方面均具有统计学意义的偏好(P<0.05)。

结论

CAD患者患髓石的可能性很高。在存在其他复合危险因素的情况下,多个牙齿中该病变的高患病率可能使此类个体成为排除CAD的候选对象。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53b7/7011460/06ed59632036/IJPVM-11-7-g001.jpg

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