Zachariah Geevar, Harikrishnan S, Krishnan M N, Mohanan P P, Sanjay G, Venugopal K, Thankappan K R
Chief Cardiologist, Mother Hospital, Thrissur, Kerala, India.
Indian Heart J. 2013 May-Jun;65(3):243-9. doi: 10.1016/j.ihj.2013.04.008. Epub 2013 Apr 9.
There is paucity of reliable contemporary data on prevalence of coronary artery disease (CAD) and risk factors in Indians. Only a few studies on prevalence of CAD have been conducted in Kerala, a Southern Indian state. The main objective of the Cardiological Society of India Kerala Chapter Coronary Artery Disease and Its Risk Factors Prevalence Study (CSI Kerala CRP Study) was to determine the prevalence of CAD and risk factors of CAD in men and women aged 20-79 years in urban and rural settings of three geographical areas of Kerala.
The design of the study was cross-sectional population survey. We estimated the sample size based on an anticipated prevalence of 7.4% of CAD for rural and 11% for urban Kerala. The derived sample sizes for rural and urban areas were 3000 and 2400, respectively. The urban areas for sampling constituted one ward each from three municipal corporations at different parts of the state. The rural sample was drawn from two panchayats each in the same districts as the urban sample. One adult from each household in the age group of 20-59 years was selected using Kish method. All subjects between 60 and 79 years were included from each household. A detailed questionnaire was administered to assess the risk factors, history of CAD, family history, educational status, socioeconomic status, dietary habits, physical activity and treatment for CAD; anthropometric measurements, blood pressure, electrocardiogram and fasting blood levels of glucose and lipids were recorded.
关于印度人冠状动脉疾病（CAD）患病率及危险因素的可靠当代数据匮乏。在印度南部喀拉拉邦，仅开展了少数几项关于CAD患病率的研究。印度心脏病学会喀拉拉邦分会冠状动脉疾病及其危险因素患病率研究（CSI喀拉拉邦CRP研究）的主要目标是确定喀拉拉邦三个地理区域城乡环境中20 - 79岁男性和女性CAD的患病率及CAD危险因素。
该研究设计为横断面人群调查。我们根据喀拉拉邦农村地区CAD预期患病率7.4%和城市地区11%来估计样本量。农村和城市地区得出的样本量分别为3000和2400。抽样的城市地区包括该邦不同地区三个市政公司的各一个选区。农村样本取自与城市样本相同地区的两个村委会。采用基什方法从每个20 - 59岁年龄组家庭中选取一名成年人。每个家庭中所有60至79岁的受试者均被纳入。通过详细问卷评估危险因素、CAD病史、家族史、教育状况、社会经济状况、饮食习惯、身体活动及CAD治疗情况；记录人体测量数据、血压、心电图以及空腹血糖和血脂水平。
