Qin Ying-Yan, Liu Zhen-Zhen, Zhu Li-Yuan, Bao Xuan, Luo Fu-Rong, Liu Yi-Zhi, Tsau Young, Wu Ming-Xing
State key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
Dimetek Digital Medical Technologies, Limited, Shenzhen 518052, Guangdong Province, China.
Int J Ophthalmol. 2020 Feb 18;13(2):284-291. doi: 10.18240/ijo.2020.02.13. eCollection 2020.
To develop a novel approach called the Autoacuity Tester, and to evaluate its validity, especially the sensitivity and specificity for detecting amblyopia.
Children aged from 3 to 12y (=552) were enrolled in the study. The validity of the Autoacuity Tester was evaluated by comparing it to the Tumbling E Early Treatment Diabetic Retinopathy Study (ETDRS) acuity chart for school age children, and Lea Symbols and Teller acuity card (TAC) for preschool children. The repeatability was assessed by coefficient of repeatability (COR). The sensitivity and specificity for detecting amblyopia were calculated.
The mean difference (95% limits of agreement) between the Autoacuity Tester and the ETDRS tests were -0.03 (-0.24, 0.19) logMAR for the school age group. In preschool children, the mean difference was 0.04 (-0.14, 0.21) logMAR between the Autoacuity Tester and the TAC and 0.00 (-0.17, 0.18) logMAR between the Autoacuity Tester and the Lea Symbols. For the school age group, the COR was 0.20 logMAR for the Autoacuity Tester and 0.18 logMAR for the ETDRS. For the preschool group, the COR was 0.13 logMAR for the Autoacuity Tester and 0.21 logMAR for TAC. The Autoacuity Tester (88%) is more sensitive than TAC (72%) in detecting amblyopia (=0.04), while had similar specificity (92% 90%, =0.20).
The Autoacuity Tester provides a reliable alternative for assessing visual acuity, and offers advantage of higher testability and repeatability for preschool children.
开发一种名为自动视力测试仪的新方法,并评估其有效性,尤其是检测弱视的敏感性和特异性。
纳入3至12岁的儿童(n = 552)参与本研究。通过将自动视力测试仪与学龄儿童的糖尿病视网膜病变早期治疗研究(ETDRS)视力表以及学龄前儿童的利雅符号和泰勒视力卡(TAC)进行比较,评估自动视力测试仪的有效性。通过重复性系数(COR)评估重复性。计算检测弱视的敏感性和特异性。
学龄组中,自动视力测试仪与ETDRS测试之间的平均差异(95%一致性界限)为-0.03(-0.24,0.19)logMAR。在学龄前儿童中,自动视力测试仪与TAC之间的平均差异为0.04(-0.14,0.21)logMAR,自动视力测试仪与利雅符号之间的平均差异为0.00(-0.17,0.18)logMAR。对于学龄组,自动视力测试仪的COR为0.20 logMAR,ETDRS为0.18 logMAR。对于学龄前组,自动视力测试仪的COR为0.13 logMAR,TAC为0.21 logMAR。自动视力测试仪(88%)在检测弱视方面比TAC(72%)更敏感(P = 0.04),而特异性相似(92%对90%,P = 0.20)。
自动视力测试仪为评估视力提供了一种可靠的替代方法,并且为学龄前儿童提供了更高的可测试性和重复性优势。