Wu Xiao-Fei, Yan Jian-Hua
The State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou 510060, Guangdong Province, China.
Int J Ophthalmol. 2020 Feb 18;13(2):349-355. doi: 10.18240/ijo.2020.02.21. eCollection 2020.
To describe the etiology, clinical characteristics, surgical options and surgical outcomes of isolated inferior oblique palsy (IOP).
A retrospective review was performed on patients with isolated IOP who were seen between January 2010 and June 2017. The following clinical data were obtained from the patients' charts: visual acuity, ocular alignment, ocular motility, cyclotorsion, stereoacuity, Parks three-step test, surgical methods, surgical outcomes and complications. Surgical success was defined as horizontal deviation ≤10 prism diopters (PD) and a vertical deviation ≤5 PD in primary gaze at both near and distant vision as assessed at last follow-up.
The records from a total of 18 patients (8 males and 10 females) with an average age of 27.56y were included in this study. The right eye was affected in 11 patients, the left in 6 patients and both eyes in 1 patient. Twelve cases (66.7%) were congenital and 6 (33.3%) were acquired IOP. The 6 acquired cases involved 2 resulting from orbital trauma/surgery, 2 from midbrain microvascular ischemia, 1 from myasthenia gravis and 1 of unknown etiology. Strabismus surgery was performed in 13 cases. Surgical techniques included weakening of superior oblique and vertical rectus recession and resection. After a mean follow-up of 15.11mo, the corrected vertical deviation in primary position was 19.92±8.52 PD (=0.000) and the corrected horizontal deviation was 14.31±12.68 PD (=0.002). The surgical success rate was 61.5% and no surgical complications were present.
Isolated IOP represents a rare condition, with most cases (66.7%) involving a congenital basis. The acquired cases included vascular, orbital trauma/surgery and myasthenia gravis. Weakening of the ipsilateral superior oblique muscle and/or contralateral superior rectus recession often resulted in favorable surgical outcomes with a surgical success rate of 61.5%.
描述孤立性下斜肌麻痹(IOP)的病因、临床特征、手术选择及手术效果。
对2010年1月至2017年6月期间诊治的孤立性IOP患者进行回顾性研究。从患者病历中获取以下临床资料:视力、眼位、眼球运动、旋转斜视、立体视锐度、帕克斯三步试验、手术方法、手术效果及并发症。手术成功定义为末次随访时在远近视力的第一眼位水平斜视度≤10棱镜度(PD)且垂直斜视度≤5 PD。
本研究纳入了18例患者(8例男性,10例女性),平均年龄27.56岁。11例患者右眼受累,6例患者左眼受累,1例患者双眼受累。12例(66.7%)为先天性IOP,6例(33.3%)为后天性IOP。6例后天性病例中,2例由眼眶外伤/手术引起,2例由中脑微血管缺血引起,1例由重症肌无力引起,1例病因不明。13例患者接受了斜视手术。手术技术包括上斜肌减弱术以及垂直直肌后徙和切除术。平均随访15.11个月后,第一眼位的垂直斜视度矫正值为19.92±8.52 PD(=0.000),水平斜视度矫正值为14.31±12.68 PD(=0.002)。手术成功率为61.5%,且无手术并发症。
孤立性IOP是一种罕见疾病,大多数病例(66.7%)为先天性。后天性病例包括血管性、眼眶外伤/手术及重症肌无力。同侧上斜肌减弱和/或对侧上直肌后徙术通常能取得良好的手术效果,手术成功率为61.5%。