School of education science, Xinyang Normal University, Xinyang 464000, China.
Key laboratory of cognition and personality (SWU), Ministry of Education, Chongqing 400715, China; Department of psychology, Southwest University, Chongqing 400715, China.
J Affect Disord. 2020 Mar 15;265:468-474. doi: 10.1016/j.jad.2020.01.086. Epub 2020 Jan 23.
Higher neuroticism personality trait individuals have more negative mood states, more sensitive to negative information, and higher risk of mental illness. Good emotion regulation ability play an important role in healthy psychological, social and physical outcomes. Previous studies have suggested that higher neuroticism individuals have a diminished ability to regulate emotion regulation. Up to now, few studies investigate the neural basis between neuroticism and emotion regulation.
In present study, we want to explore the neuroticism and the activity of some brain regions and functional amygdala connectivity (psycho-physiological interaction [PPI]) in a cognitive reappraisal task. Thus, 160 healthy young participants were scanned during a cognitive reappraisal task.
The results revealed that neuroticism scores showed a significant negative association with the activity of the dorsomedial prefrontal cortex (dmPFC), inferior frontal cortex and middle frontal cortex in regulation of negative emotion. PPI analyses revealed that neuroticism scores were negatively associated with amygdala-dmPFC connectivity in regulation of negative emotion.
Only cognitive reappraisal were investigated in this study. Other emotion regulation strategies such as expressive suppression need to be explored in the future study.
These results may suggest that highly neurotic participants display diminished cognitive reappraisal and diminished control function of the dmPFC over the amygdala in regulation of negative emotion.
高神经质人格特质的个体情绪状态更消极，对负面信息更敏感，患精神疾病的风险更高。良好的情绪调节能力对健康的心理、社会和生理结果起着重要作用。先前的研究表明，高神经质个体的情绪调节能力减弱。到目前为止，很少有研究探讨神经质和情绪调节之间的神经基础。
在本研究中，我们想在认知重评任务中探索神经质和一些大脑区域的活动以及杏仁核功能连接（心理生理交互作用[PPI]）之间的关系。因此，我们对 160 名健康的年轻参与者进行了认知重评任务的扫描。
结果表明，神经质得分与负性情绪调节时背内侧前额叶皮质（dmPFC）、下额前皮质和中额前皮质的活动呈显著负相关。PPI 分析表明，神经质得分与负性情绪调节时杏仁核-dmPFC 连接呈负相关。
本研究仅探讨了认知重评。未来的研究需要探索其他情绪调节策略，如表达抑制。
这些结果可能表明，高神经质的参与者在负性情绪调节中表现出认知重评能力减弱和 dmPFC 对杏仁核的控制功能减弱。
