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局部变应性鼻炎:鼻过敏原激发试验作为鉴别诊断的良好工具。

Local allergic rhinitis: nasal allergen provocation testing as a good tool in the differential diagnosis.

作者信息

Wojas Oksana, Samoliński Bolesław Krzysztof, Krzych-Fałta Edyta

机构信息

Medical University of Warsaw, Warsaw, Poland (Faculty of Health Sciences, Department of the Environmental Hazards Prevention and Allergology).

出版信息

Int J Occup Med Environ Health. 2020 Mar 13;33(2):241-246. doi: 10.13075/ijomeh.1896.01503. Epub 2020 Feb 24.

DOI:10.13075/ijomeh.1896.01503
PMID:32091011
Abstract

Local allergic rhinitis (LAR) is a specific phenotype of allergic rhinitis. One characteristic feature of LAR is a medical history indicative of an allergic disease, negative skin-prick test results, undetectable levels of specific IgE, and a positive allergen-specific nasal provocation test. This paper presents a case of a patient with LAR and underlying house dust mite allergy, who was ultimately diagnosed >10 years after the onset of his first symptoms. Currently, there are only pharmacological treatments available for LAR. However, some studies show encouraging results with the use of allergen-specific immunotherapy in LAR, which offer hope for a future use of this causative treatment in LAR patients. Int J Occup Med Environ Health. 2020;33(2):241-6.

摘要

局部变应性鼻炎(LAR)是变应性鼻炎的一种特定表型。LAR的一个特征是有过敏性疾病的病史、皮肤点刺试验结果为阴性、特异性IgE水平检测不到以及变应原特异性鼻激发试验呈阳性。本文介绍了一例患有LAR且对屋尘螨过敏的患者,该患者在首次出现症状10多年后最终确诊。目前,LAR仅有药物治疗方法。然而,一些研究表明,在LAR中使用变应原特异性免疫疗法取得了令人鼓舞的结果,这为未来在LAR患者中使用这种病因性治疗带来了希望。《国际职业医学与环境卫生杂志》。2020年;33(2):241 - 6。

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