小干扰RNA疗法的药物递送
Drug Delivery of siRNA Therapeutics.
作者信息
Lamberti Gaetano, Barba Anna Angela
机构信息
Eng4Life Srl, Spin-off Accademico, Via Fiorentino, 32, 83100 Avellino, Italy.
Dipartimento di Ingegneria Industriale; Università degli Studi di Salerno, via Giovanni Paolo II, 132 84084 Fisciano (SA), Italy.
出版信息
Pharmaceutics. 2020 Feb 20;12(2):178. doi: 10.3390/pharmaceutics12020178.
Abstract
Small interfering RNA (siRNA) is a class of nucleic acid-based drugs (NABDs) able to block gene expression by interaction with mRNA before its translation [...].
摘要
小干扰RNA（siRNA）是一类基于核酸的药物（NABDs），能够在mRNA翻译前通过与mRNA相互作用来阻断基因表达[……]。
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