Darouti E, Rubaie A
Department of Dermatology, Seif Bin Gubash Hospital, United Arab Emirates.
Int J Dermatol. 1988 Oct;27(8):593-5. doi: 10.1111/j.1365-4362.1988.tb02413.x.
Twenty-one patients with severe psoriasis involving more than 40% of the body surface were included in the first controlled study of RePUVA therapy in the United Arab Emirates. The control group was given PUVA only. In the RePUVA group, PUVA was started with the retinoids (not following the retinoids by 2 weeks as is usually done in the standard RePUVA therapy) and then was gradually increased, so it was possible to give 4 j/cm2 by the beginning of the third week. Administration of PUVA in this way would save the time needed to reach an effective PUVA dose if the latter is started 2 weeks following oral retinoids.
21名银屑病面积超过体表面积40%的重度银屑病患者被纳入阿联酋首次RePUVA疗法对照研究。对照组仅接受PUVA治疗。在RePUVA组中,PUVA治疗与维甲酸同时开始(不像标准RePUVA疗法那样在维甲酸治疗2周后再开始),然后逐渐增加剂量,因此在第三周开始时就有可能给予4J/cm²的剂量。如果在口服维甲酸2周后开始PUVA治疗,采用这种方式给予PUVA可节省达到有效PUVA剂量所需的时间。