Thirumoorthy T, Rajan V S
Ann Acad Med Singap. 1983 Jan;12(1):39-44.
New treatment modalities are now available in the management of psoriasis. We report our local studies on these new modalities. Application of dithranol for 1/2 hour is just as effective as when applied for 24 hours. This means less staining of the skin, clothes and no more burns. Oral retinoids gave more than 70% improvement in six of the seven patients with recalcitrant psoriasis. Oral retinoids produced more than 75% improvement in all eight patients with pustular psoriasis. PUVA therapy gave a complete clearance rate of 77% with an average of 25 sessions of treatment and an average total UVA dose of 346 J/cm2. However REPUVA (retinoids and PUVA) produced a complete clearance rate of 73% with an average of 18 sessions of treatment and an average total UVA dose of 142 J/cm2. The newer forms of treatment together with the established therapies have tremendously improved the total management of patients with psoriasis.
目前在银屑病的治疗中已有新的治疗方式。我们报告我们在这些新方式方面的本地研究。蒽林应用半小时与应用24小时的效果一样。这意味着对皮肤、衣物的染色更少，且不会再有灼伤。口服维甲酸使7例顽固性银屑病患者中的6例改善超过70%。口服维甲酸使所有8例脓疱型银屑病患者的改善超过75%。光化学疗法（PUVA）平均治疗25次、平均总UVA剂量为346 J/cm²时，完全清除率为77%。然而，联合维甲酸的光化学疗法（REPUVA）平均治疗18次、平均总UVA剂量为142 J/cm²时，完全清除率为73%。这些新的治疗方式与既定疗法一起极大地改善了银屑病患者的整体治疗。
