National Center for Natural Products Research, School of Pharmacy, University of Mississippi, University Park, Mississippi, USA.
Division of Pharmacognosy, Department of BioMolecular Sciences, School of Pharmacy, University of Mississippi, University Park, Mississippi, USA.
Nat Prod Res. 2021 Nov;35(21):3707-3713. doi: 10.1080/14786419.2020.1731743. Epub 2020 Feb 24.
seeds are widely used as a spice in Africa. Two undescribed paradol-related compounds, ()-9-hydroxy-[6]-paradol () and (9)-3,9-dihydroxydihydro-[6]-paradol () together with eight reported constituents () were isolated and characterised from the methanol extract of seeds. Structure elucidation of these metabolites was achieved by means of NMR and mass spectroscopic data analyses. The absolute configuration of undescribed compounds ( and ) was determined using the modified Mosher's method.
种子在非洲被广泛用作香料。从 种子的甲醇提取物中分离并鉴定出两种未描述的与 paradoxol 相关的化合物(()-9-羟基-[6]-paradol () 和 (9)-3,9-二羟基二氢-[6]-paradol ())以及八种报道的成分()。这些代谢物的结构通过 NMR 和质谱数据分析来阐明。使用改进的 Mosher 法确定了未描述化合物(和)的绝对构型。