Zaias N, Battistini F
Arch Dermatol. 1977 Mar;113(3):307-8. doi: 10.1001/archderm.113.3.307.
A 1% clotrimazole solution was used as an antifungal for Tinea versicolor, Cutaneous Candidiasis and Dermatophytosis. All studies were double-blind and controlled, active vs vehicle. The final evaluation was made at a two-week follow-up after the treatment was stopped, which for most of the clinical conditions studied, was 28 days. The 1% clotrimazole solution was found to be effective with no local irritation noted.
1%克霉唑溶液用作治疗花斑癣、皮肤念珠菌病和皮肤癣菌病的抗真菌药物。所有研究均为双盲对照试验,活性药物与赋形剂对照。在停药后两周进行最终评估,对于大多数所研究的临床病症而言,即停药28天后进行评估。结果发现1%克霉唑溶液有效,且未观察到局部刺激现象。