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咪康唑与克霉唑治疗浅表真菌病的对比研究。

Comparative study of miconazole and clotrimazole in superficial mycosis.

作者信息

Saha K C

出版信息

Indian J Dermatol. 1989 Sep;34(3):69-72.

PMID:2632381
Abstract

Two hundred cases of superficial mycosis (100 dermatophytosis, 40 candidiasis and 60 pityriasis versicolor) were studied for the comparative effect of miconazole and clotrimazole. The patients were evaluated both clinically and mycologically every 2 weeks for a period of 12 weeks. In dermatophytosis, miconazole showed accelerated response (75% cleared in 6 weeks) than clotrimazole (56%). In candidiasis, both were found to be effective (80-85%) cure though clotrimazole showed slightly earlier response (40% cure in 6 weeks) against miconazole (30% cure). In pityriasis versicolor both were, effective (miconazole 99.6% and clotrimazole 86.7%).

摘要

对200例浅表真菌病(100例皮肤癣菌病、40例念珠菌病和60例花斑糠疹)进行了咪康唑和克霉唑对比疗效研究。患者每2周进行一次临床和真菌学评估,为期12周。在皮肤癣菌病中,咪康唑的反应速度更快(6周内75%清除),高于克霉唑(56%)。在念珠菌病中,两者均被发现有效(治愈率80 - 85%),尽管克霉唑对咪康唑(治愈率30%)显示出稍早的反应(6周内治愈率40%)。在花斑糠疹中,两者均有效(咪康唑99.6%,克霉唑86.7%)。

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