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产科人群中的硬脊膜穿破后头痛:新方法?

Postdural puncture headache in the obstetric population: a new approach?

机构信息

Serviço de Anestesiologia - Departamento de Anestesiologia Cuidados Intensivos e Emergencia, Centro Hospitalar e Universitário do Porto, Porto, Portugal

Serviço de Anestesiologia - Departamento de Anestesiologia Cuidados Intensivos e Emergencia, Centro Hospitalar e Universitário do Porto, Porto, Portugal.

出版信息

Reg Anesth Pain Med. 2020 May;45(5):373-376. doi: 10.1136/rapm-2019-101053. Epub 2020 Feb 23.

Abstract

BACKGROUND AND OBJECTIVES

The gold standard for the treatment of postdural puncture headache (PDPH) is the epidural blood patch (EBP). Regional techniques-sphenopalatine ganglion block (SPGB), greater occipital nerve block (GONB) and trigger point infiltration (TPI)-can also be used for the treatment of PDPH. Our objective was to evaluate the efficacy of these peripheral nerve blocks (PNBs) in the treatment of PDPH.

METHODS

A retrospective study was conducted including all patients with PDPH in the obstetrics department of our institution between April 2016 and December 2017. Data were retrieved from clinical records regarding anesthetic technique, symptoms, treatment, Numeric Pain Score (NPS) before and after treatment, among others.

RESULTS

We observed 50 cases of PDPH: 25 following spinal anesthesia, 19 following epidural block and 6 following combined spinal-epidural. Of these, seven were managed conservatively and one received EBP as first-line treatment. The remaining 42 patients received PNB as first-line treatment. Of these, 27 received only 1 course of PNB, while 15 received 2 courses. We observed a statistically significant improvement in the NPS after the first course of blocks (n=42), with a reduction of the median NPS by 6.0 (IQR 4.0-7.5; p<0.001). Improvement was also observed after the second course of blocks (n=15), with a reduction of the median NPS of 3.5 (IQR 1.5-5.0; p=0.02). Due to treatment failure, 9 of the 42 patients treated with PNB required EBP. None of these were cases following spinal anesthesia.

CONCLUSION

SPGB, GONB and TPI can be safe and effective options for treatment of PDPH, but do not completely eliminate the need for EBP. Prospective studies designed to identify factors associated with unsuccessful treatment are required.

摘要

背景与目的

硬膜穿破后头痛(PDPH)的治疗金标准是硬膜外血贴(EBP)。局部技术-蝶腭神经节阻滞(SPGB)、枕大神经阻滞(GONB)和触发点浸润(TPI)-也可用于治疗 PDPH。我们的目的是评估这些周围神经阻滞(PNB)治疗 PDPH 的疗效。

方法

我们进行了一项回顾性研究,纳入了 2016 年 4 月至 2017 年 12 月期间我院产科所有 PDPH 患者。从临床记录中检索了与麻醉技术、症状、治疗、治疗前后数字疼痛评分(NPS)等相关的数据。

结果

我们观察到 50 例 PDPH:25 例与脊髓麻醉有关,19 例与硬膜外阻滞有关,6 例与联合脊髓-硬膜外阻滞有关。其中 7 例接受保守治疗,1 例接受 EBP 作为一线治疗。其余 42 例患者接受 PNB 作为一线治疗。其中 27 例仅接受 1 个疗程 PNB,15 例接受 2 个疗程。我们观察到在接受第 1 个疗程的阻滞治疗后(n=42),NPS 有统计学意义的改善,中位数 NPS 降低了 6.0(IQR 4.0-7.5;p<0.001)。在接受第 2 个疗程的阻滞治疗后(n=15),NPS 也有所改善,中位数 NPS 降低了 3.5(IQR 1.5-5.0;p=0.02)。由于治疗失败,42 例接受 PNB 治疗的患者中有 9 例需要 EBP。这些患者均无脊髓麻醉后病例。

结论

SPGB、GONB 和 TPI 可以是治疗 PDPH 的安全有效选择,但不能完全消除对 EBP 的需求。需要设计前瞻性研究来确定与治疗失败相关的因素。

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