Wang Xiao Yan, Liu Zi Jing, Zhang Jia Wen, Liu Yun Yi, Wang Da-Guang, Xu Yang
Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, China.
Case Rep Dermatol Med. 2020 Feb 11;2020:2391907. doi: 10.1155/2020/2391907. eCollection 2020.
Syphilis is a sexually transmitted disease caused by . The signs and symptoms of syphilis vary depending on which of the four stages it presents. The primary stage of syphilis classically presents with a painless ulcer (chancre). We report a case of the extragenital chancre on the nipple which is examined from skin biopsy and immunohistochemistry. This case showed that it is important to identify the special site's pruritus erythema by pathology and serological examination.
梅毒是一种由……引起的性传播疾病。梅毒的体征和症状因呈现的四个阶段中的哪一个阶段而异。梅毒的一期典型表现为无痛性溃疡（硬下疳）。我们报告一例乳头部位发生的生殖器外硬下疳病例，该病例通过皮肤活检和免疫组织化学进行了检查。此病例表明，通过病理学和血清学检查来识别特殊部位的瘙痒性红斑很重要。
