Gandhi S, Behling E, Behrens D, Ferber A, Schwarting R, Budak-Alpdogan T
MD Anderson Cancer Center at Cooper, Camden, NJ, USA.
Department of Pathology, Cooper University Hospital, Camden, NJ, USA.
Case Rep Transplant. 2020 Feb 10;2020:8247308. doi: 10.1155/2020/8247308. eCollection 2020.
The posttransplant lymphoproliferative disorders (PTLDs) are a heterogeneous group of neoplasms that have wide variety of clinical and histological presentations. The management of PTLDs is challenging due to variety of involvement sites and histological types. The length and type of immunosuppression are correlated with the emergence of PTLDs, and most of the cases appear within the first two years after transplant. This case series describes five late-onset PTLDs with rare histological features and multiorgan involvement.
移植后淋巴细胞增生性疾病（PTLDs）是一组异质性肿瘤，具有多种多样的临床和组织学表现。由于受累部位和组织学类型的多样性，PTLDs的管理具有挑战性。免疫抑制的时长和类型与PTLDs的出现相关，且大多数病例出现在移植后的头两年内。本病例系列描述了5例具有罕见组织学特征和多器官受累的迟发性PTLDs。
