全球层面菌株的多样性及其决定因素。
Diversity of strains at the global level and its determinants.
作者信息
Galal L, Hamidović A, Dardé M L, Mercier M
机构信息
INSERM, Univ. Limoges, CHU Limoges, UMR 1094, Institut d'Epidémiologie et de Neurologie Tropicale, GEIST, 87000 Limoges, France.
Centre National de Référence Toxoplasmose/Toxoplasma Biological Resource Center, CHU Limoges, 87042 Limoges, France.
出版信息
Food Waterborne Parasitol. 2019 Apr 1;15:e00052. doi: 10.1016/j.fawpar.2019.e00052. eCollection 2019 Jun.
Abstract
The population structure of is characterized by contrasting geographic patterns of strain diversity at different spatial scales: global, regional and even local scales in some regions. The determinants of this diversity pattern and its possible evolutionary mechanisms are still largely unexplored. This review will focus on three main dichotomies observed in the population structure of the parasite: (1) domestic wild, (2) South America the rest of the world and (3) intercontinental clonal lineages regional or local clonal lineages. Here, the impact in terms of public health of this remarkably contrasting geographic diversity of populations is discussed, with emphasis on the role of globalization of exchanges that could lead to rapid evolution of population spatial structure and new challenges in a One Health context.
摘要
[寄生虫名称]的种群结构具有不同空间尺度（全球、区域，甚至某些地区的局部尺度）上菌株多样性的对比鲜明的地理模式特征。这种多样性模式的决定因素及其可能的进化机制在很大程度上仍未得到探索。本综述将聚焦于在该寄生虫种群结构中观察到的三个主要二分法：（1）家养的与野生的，（2）南美洲与世界其他地区，以及（3）洲际克隆谱系与区域或局部克隆谱系。在此，讨论了[寄生虫名称]种群这种显著对比的地理多样性对公共卫生的影响，重点强调了交流全球化的作用，其可能导致[寄生虫名称]种群空间结构的快速进化以及在“同一健康”背景下带来新的挑战。
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